Keng B. Wee

1 Fusionopolis Way
Paraguay

Last Updated: 09/26/2026

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Found 25 publications

A synergistic interaction between PRMT5 and LSD1 inhibitors in AML.

A synergistic interaction between PRMT5 and LSD1 inhibitors in AML.

Journal: Science advances

Published: March 27, 2026

Spliceosome induction is a druggable dependency of RAS-driven senescence and cancer.

Spliceosome induction is a druggable dependency of RAS-driven senescence and cancer.

Journal: Nature communications

Published: November 24, 2025

BLOC1S1 depletion via splice-switching oligonucleotides improves mitochondrial respiration and rescues ALS phenotypes.

BLOC1S1 depletion via splice-switching oligonucleotides improves mitochondrial respiration and rescues ALS phenotypes.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy

Published: August 12, 2025

A programmable ribozyme for RNA signal transduction.

A programmable ribozyme for RNA signal transduction.

Journal: Nature communications

Published: March 13, 2025

Utargetome: A targetome prediction tool for modified U1-snRNAs to identify distal-target positions with improved selectivity.

Utargetome: A targetome prediction tool for modified U1-snRNAs to identify distal-target positions with improved selectivity.

Journal: PLoS computational biology

Published: November 19, 2024

A splice-switch oligonucleotide loaded self-cleavable DNA nanogel.

A splice-switch oligonucleotide loaded self-cleavable DNA nanogel.

Journal: Chemical communications (Cambridge, England)

Published: September 23, 2024

Developing splice-switching oligonucleotides for urea cycle disorder using an integrated diagnostic and therapeutic platform.

Developing splice-switching oligonucleotides for urea cycle disorder using an integrated diagnostic and therapeutic platform.

Journal: Journal of hepatology

Published: July 08, 2024

Unveiling sequence-agnostic mixed-chemical modification patterns for splice-switching oligonucleotides using the NATURA platform.

Unveiling sequence-agnostic mixed-chemical modification patterns for splice-switching oligonucleotides using the NATURA platform.

Journal: Molecular therapy. Nucleic acids

Published: June 13, 2024

Nature-inspired platform nanotechnology for RNA delivery to myeloid cells and their bone marrow progenitors.

Nature-inspired platform nanotechnology for RNA delivery to myeloid cells and their bone marrow progenitors.

Journal: Nature nanotechnology

Published: October 17, 2023

RBFOX2 deregulation promotes pancreatic cancer progression and metastasis through alternative splicing.

RBFOX2 deregulation promotes pancreatic cancer progression and metastasis through alternative splicing.

Journal: Nature communications

Published: August 02, 2022

Splice-switch oligonucleotide-based combinatorial platform prioritizes synthetic lethal targets CHK1 and BRD4 against MYC-driven hepatocellular carcinoma.

Splice-switch oligonucleotide-based combinatorial platform prioritizes synthetic lethal targets CHK1 and BRD4 against MYC-driven hepatocellular carcinoma.

Journal: Bioengineering & translational medicine

Published: April 19, 2022

Splice-Switching Antisense Oligonucleotides as a Targeted Intrinsic Engineering Tool for Generating Armored Redirected T Cells.

Splice-Switching Antisense Oligonucleotides as a Targeted Intrinsic Engineering Tool for Generating Armored Redirected T Cells.

Journal: Nucleic acid therapeutics

Published: February 10, 2021

Showing 1-12 of 25

Last Updated: 09/26/2026