Kengo Homma

Yokohama, Japan

Last Updated: 09/26/2026

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Found 13 publications

Induced pluripotent stem cell-based assays recapture multiple properties of human astrocytes.

Induced pluripotent stem cell-based assays recapture multiple properties of human astrocytes.

Journal: Journal of cellular and molecular medicine

Published: September 22, 2023

Histopathological changes of the spinal cord and motor neuron dynamics in SOD1 Tg mice.

Histopathological changes of the spinal cord and motor neuron dynamics in SOD1 Tg mice.

Journal: Journal of toxicologic pathology

Published: September 02, 2021

ASK1 promotes uterine inflammation leading to pathological preterm birth.

ASK1 promotes uterine inflammation leading to pathological preterm birth.

Journal: Scientific reports

Published: August 28, 2019

Genome-wide siRNA screening reveals that DCAF4-mediated ubiquitination of optineurin stimulates autophagic degradation of Cu,Zn-superoxide dismutase.

Genome-wide siRNA screening reveals that DCAF4-mediated ubiquitination of optineurin stimulates autophagic degradation of Cu,Zn-superoxide dismutase.

Journal: The Journal of biological chemistry

Published: July 18, 2019

A small-molecule inhibitor of SOD1-Derlin-1 interaction ameliorates pathology in an ALS mouse model.

A small-molecule inhibitor of SOD1-Derlin-1 interaction ameliorates pathology in an ALS mouse model.

Journal: Nature communications

Published: June 18, 2017

Zinc depletion and ER stress

Zinc depletion and ER stress

Journal: Nihon rinsho. Japanese journal of clinical medicine

Published: July 27, 2016

SOD1 in neurotoxicity and its controversial roles in SOD1 mutation-negative ALS.

SOD1 in neurotoxicity and its controversial roles in SOD1 mutation-negative ALS.

Journal: Advances in biological regulation

Published: September 24, 2015

The ASK1-specific inhibitors K811 and K812 prolong survival in a mouse model of amyotrophic lateral sclerosis.

The ASK1-specific inhibitors K811 and K812 prolong survival in a mouse model of amyotrophic lateral sclerosis.

Journal: Human molecular genetics

Published: July 06, 2015

Inhibition of Cytohesins Protects against Genetic Models of Motor Neuron Disease.

Inhibition of Cytohesins Protects against Genetic Models of Motor Neuron Disease.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience

Published: June 19, 2015

The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis.

The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis.

Journal: Science translational medicine

Published: April 15, 2015

A systematic immunoprecipitation approach reinforces the concept of common conformational alterations in amyotrophic lateral sclerosis-linked SOD1 mutants.

A systematic immunoprecipitation approach reinforces the concept of common conformational alterations in amyotrophic lateral sclerosis-linked SOD1 mutants.

Journal: Neurobiology of disease

Published: March 24, 2015

SOD1 as a molecular switch for initiating the homeostatic ER stress response under zinc deficiency.

SOD1 as a molecular switch for initiating the homeostatic ER stress response under zinc deficiency.

Journal: Molecular cell

Published: August 06, 2012

Showing 1-12 of 13

Last Updated: 09/26/2026