Kenneth A. Simmen
Beerse, VLG 2340, Belgium
Last Updated: 09/26/2026
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Found 10 publications
Characterization of a dengue NS4B inhibitor originating from an HCV small molecule library.
Journal: Antiviral research
Published: April 07, 2017
Synthesis and evaluation of novel HCV replication inhibitors.
Journal: Molecular diversity
Published: October 13, 2016
Safety and pharmacokinetics of the HIV-1 protease inhibitor TMC310911 coadministered with ritonavir in healthy participants: results from 2 phase 1 studies.
Journal: Journal of acquired immune deficiency syndromes (1999)
Published: October 15, 2013
Antiviral activity, pharmacokinetics, and safety of the HIV-1 protease inhibitor TMC310911, coadministered with ritonavir, in treatment-naive HIV-1-infected patients.
Journal: Journal of acquired immune deficiency syndromes (1999)
Published: October 15, 2013
TMC647055, a potent nonnucleoside hepatitis C virus NS5B polymerase inhibitor with cross-genotypic coverage.
Journal: Antimicrobial agents and chemotherapy
Published: June 20, 2012
Finger-loop inhibitors of the HCV NS5b polymerase. Part 1: Discovery and optimization of novel 1,6- and 2,6-macrocyclic indole series.
Journal: Bioorganic & medicinal chemistry letters
Published: February 24, 2012
Discovery of 4'-azido-2'-deoxy-2'-C-methyl cytidine and prodrugs thereof: a potent inhibitor of Hepatitis C virus replication.
Journal: Bioorganic & medicinal chemistry letters
Published: January 26, 2012
Efficacy of re-treatment with TMC435 as combination therapy in hepatitis C virus-infected patients following TMC435 monotherapy.
Journal: Gastroenterology
Published: December 14, 2011
Rapid viral response of once-daily TMC435 plus pegylated interferon/ribavirin in hepatitis C genotype-1 patients: a randomized trial.
Journal: Antiviral therapy
Published: October 26, 2011
Showing 1-10 of 10
Last Updated: 09/26/2026