Kenneth Lay

Singapore, Singapore

Last Updated: 09/26/2026

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Found 12 publications

DPP9 deficiency: An inflammasomopathy that can be rescued by lowering NLRP1/IL-1 signaling.

DPP9 deficiency: An inflammasomopathy that can be rescued by lowering NLRP1/IL-1 signaling.

Journal: Science immunology

Published: September 16, 2022

A homozygous p.Leu813Pro gain-of-function NLRP1 variant causes phenotypes of different severity in two siblings.

A homozygous p.Leu813Pro gain-of-function NLRP1 variant causes phenotypes of different severity in two siblings.

Journal: The British journal of dermatology

Published: June 14, 2022

Stem cells expand potency and alter tissue fitness by accumulating diverse epigenetic memories.

Stem cells expand potency and alter tissue fitness by accumulating diverse epigenetic memories.

Journal: Science (New York, N.Y.)

Published: November 25, 2021

Human NLRP1 is a sensor of pathogenic coronavirus 3CL proteases in lung epithelial cells.

Human NLRP1 is a sensor of pathogenic coronavirus 3CL proteases in lung epithelial cells.

Journal: Molecular cell

Published: October 19, 2021

Loss of FOCAD, operating via the SKI messenger RNA surveillance pathway, causes a pediatric syndrome with liver cirrhosis.

Loss of FOCAD, operating via the SKI messenger RNA surveillance pathway, causes a pediatric syndrome with liver cirrhosis.

Journal: Nature genetics

Published: October 11, 2021

Structural basis for distinct inflammasome complex assembly by human NLRP1 and CARD8.

Structural basis for distinct inflammasome complex assembly by human NLRP1 and CARD8.

Journal: Nature communications

Published: April 03, 2020

Enteroviral 3C protease activates the human NLRP1 inflammasome in airway epithelia.

Enteroviral 3C protease activates the human NLRP1 inflammasome in airway epithelia.

Journal: Science (New York, N.Y.)

Published: June 20, 2019

Stem cells repurpose proliferation to contain a breach in their niche barrier.

Stem cells repurpose proliferation to contain a breach in their niche barrier.

Journal: eLife

Published: September 02, 2018

FOXC1 maintains the hair follicle stem cell niche and governs stem cell quiescence to preserve long-term tissue-regenerating potential.

FOXC1 maintains the hair follicle stem cell niche and governs stem cell quiescence to preserve long-term tissue-regenerating potential.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: February 26, 2016

In vivo transcriptional governance of hair follicle stem cells by canonical Wnt regulators.

In vivo transcriptional governance of hair follicle stem cells by canonical Wnt regulators.

Journal: Nature cell biology

Published: July 01, 2013

A comprehensive analysis of the effects of the deaminase AID on the transcriptome and methylome of activated B cells.

A comprehensive analysis of the effects of the deaminase AID on the transcriptome and methylome of activated B cells.

Journal: Nature immunology

Published: January 26, 2013

NOVA-dependent regulation of cryptic NMD exons controls synaptic protein levels after seizure.

NOVA-dependent regulation of cryptic NMD exons controls synaptic protein levels after seizure.

Journal: eLife

Published: August 22, 2012

Showing 1-12 of 12

Last Updated: 09/26/2026