Kevin D. Read

Dundee, SCT DD15EH, United Kingdom

Last Updated: 09/26/2026

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Found 102 publications

Structure-Guided Optimization of Novel Inhibitors of Plasmodium Lysyl-tRNA Synthetase with Multistage Activity against Malaria Parasites.

Structure-Guided Optimization of Novel Inhibitors of Plasmodium Lysyl-tRNA Synthetase with Multistage Activity against Malaria Parasites.

Journal: Journal of medicinal chemistry
Published: June 02, 2026

Identification and Evaluation of Dibasic Piperidines as Cell Wall Inhibitors against Mycobacterium tuberculosis.

Identification and Evaluation of Dibasic Piperidines as Cell Wall Inhibitors against Mycobacterium tuberculosis.

Journal: ACS infectious diseases
Published: May 14, 2026

5‑Nitrofuran-Semicarbazone Hybrids as Antitrypanosomal Agents: Structure-Activity Relationship and Nitroreductase Activation.

5‑Nitrofuran-Semicarbazone Hybrids as Antitrypanosomal Agents: Structure-Activity Relationship and Nitroreductase Activation.

Journal: ACS medicinal chemistry letters
Published: April 13, 2026

Use of a cytochrome P450 humanized mouse model to refine schistosomiasis drug discovery.

Use of a cytochrome P450 humanized mouse model to refine schistosomiasis drug discovery.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: April 10, 2026

Identification and Evaluation of dibasic piperidines as novel cell wall inhibitors against Mycobacterium tuberculosis.

Identification and Evaluation of dibasic piperidines as novel cell wall inhibitors against Mycobacterium tuberculosis.

Journal: bioRxiv : the preprint server for biology
Published: February 26, 2026

Humanization of Drug Metabolism in the Plasmodium berghei Mouse Model for Antimalarial Drug Discovery.

Humanization of Drug Metabolism in the Plasmodium berghei Mouse Model for Antimalarial Drug Discovery.

Journal: ACS infectious diseases
Published: December 01, 2025

Small molecule inhibitors of the NorA multidrug efflux pump potentiate antibiotic activity by binding the outward-open conformation.

Small molecule inhibitors of the NorA multidrug efflux pump potentiate antibiotic activity by binding the outward-open conformation.

Journal: bioRxiv : the preprint server for biology
Published: September 02, 2025

Design and Development of Lysyl tRNA Synthetase Inhibitors, for the Treatment of Tuberculosis.

Design and Development of Lysyl tRNA Synthetase Inhibitors, for the Treatment of Tuberculosis.

Journal: Journal of medicinal chemistry
Published: August 01, 2025

Open-science discovery of DNDI-6510, a compound that addresses genotoxic and metabolic liabilities of the COVID Moonshot SARS-CoV-2 Mpro lead inhibitor.

Open-science discovery of DNDI-6510, a compound that addresses genotoxic and metabolic liabilities of the COVID Moonshot SARS-CoV-2 Mpro lead inhibitor.

Journal: bioRxiv : the preprint server for biology
Published: July 16, 2025

Untargeted metabolomics for triaging of cytochrome b inhibitors during Chagas' disease drug discovery.

Untargeted metabolomics for triaging of cytochrome b inhibitors during Chagas' disease drug discovery.

Journal: PLoS neglected tropical diseases
Published: July 02, 2025

High-Throughput Screening of Potent Drug-like Molecules Targeting 17β-HSD10 for the Treatment of Alzheimer's Disease and Cancer.

High-Throughput Screening of Potent Drug-like Molecules Targeting 17β-HSD10 for the Treatment of Alzheimer's Disease and Cancer.

Journal: ACS chemical biology
Published: June 18, 2025

Application of a mouse model humanized for cytochrome P450-mediated drug metabolism to predict drug-drug interactions between a peptide and small molecule drugs.

Application of a mouse model humanized for cytochrome P450-mediated drug metabolism to predict drug-drug interactions between a peptide and small molecule drugs.

Journal: Drug metabolism and disposition: the biological fate of chemicals
Published: June 06, 2025
Showing 1-12 of 102

Last Updated: 09/26/2026