Kevin Kos

Leiden, ZH, Netherlands

Last Updated: 09/26/2026

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Found 13 publications

NK cell heparanase controls tumor invasion and immune surveillance.

NK cell heparanase controls tumor invasion and immune surveillance.

Journal: The Journal of clinical investigation
Published: July 01, 2024

Neoadjuvant immune checkpoint blockade triggers persistent and systemic Treg activation which blunts therapeutic efficacy against metastatic spread of breast tumors.

Neoadjuvant immune checkpoint blockade triggers persistent and systemic Treg activation which blunts therapeutic efficacy against metastatic spread of breast tumors.

Journal: Oncoimmunology
Published: April 24, 2023

Tumor-associated macrophages promote intratumoral conversion of conventional CD4+ T cells into regulatory T cells via PD-1 signalling.

Tumor-associated macrophages promote intratumoral conversion of conventional CD4+ T cells into regulatory T cells via PD-1 signalling.

Journal: Oncoimmunology
Published: April 28, 2022

IL-5-producing CD4+ T cells and eosinophils cooperate to enhance response to immune checkpoint blockade in breast cancer.

IL-5-producing CD4+ T cells and eosinophils cooperate to enhance response to immune checkpoint blockade in breast cancer.

Journal: Cancer cell
Published: March 01, 2022

Pro-mutagenic effects of the gut microbiota in a Lynch syndrome mouse model.

Pro-mutagenic effects of the gut microbiota in a Lynch syndrome mouse model.

Journal: Gut microbes
Published: February 21, 2022

The Multifaceted Role of Regulatory T Cells in Breast Cancer.

The Multifaceted Role of Regulatory T Cells in Breast Cancer.

Journal: Annual review of cancer biology
Published: October 11, 2021

Tumor-educated Tregs drive organ-specific metastasis in breast cancer by impairing NK cells in the lymph node niche.

Tumor-educated Tregs drive organ-specific metastasis in breast cancer by impairing NK cells in the lymph node niche.

Journal: Cell reports
Published: March 23, 2021

Neutrophils create a fertile soil for metastasis.

Neutrophils create a fertile soil for metastasis.

Journal: Cancer cell
Published: January 29, 2021

Flow cytometry-based isolation of tumor-associated regulatory T cells and assessment of their suppressive potential.

Flow cytometry-based isolation of tumor-associated regulatory T cells and assessment of their suppressive potential.

Journal: Methods in enzymology
Published: February 01, 2020

Therapeutic targeting of macrophages enhances chemotherapy efficacy by unleashing type I interferon response.

Therapeutic targeting of macrophages enhances chemotherapy efficacy by unleashing type I interferon response.

Journal: Nature cell biology
Published: December 14, 2018

NK cell heparanase controls tumor invasion and immune surveillance.

NK cell heparanase controls tumor invasion and immune surveillance.

Journal: The Journal of clinical investigation
Published: January 20, 2017

Targeting cytokine signaling checkpoint CIS activates NK cells to protect from tumor initiation and metastasis.

Targeting cytokine signaling checkpoint CIS activates NK cells to protect from tumor initiation and metastasis.

Journal: Oncoimmunology
Published: September 02, 2016
Showing 1-12 of 13

Last Updated: 09/26/2026