Kevin Smart
Welwyn, ENG, United Kingdom
Last Updated: 09/26/2026
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Found 11 publications
Safety and Antitumor Activity of a Novel aCD25 Treg Depleter RG6292 as a Single Agent and in Combination with Atezolizumab in Patients with Solid Tumors.
Journal: Cancer research communications
Published: January 02, 2025
Development of a population pharmacokinetic model to characterize the pharmacokinetics of intrathecally administered tominersen in cerebrospinal fluid and plasma.
Journal: CPT: pharmacometrics & systems pharmacology
Published: January 02, 2023
PK/PD Mediated Dose Optimization of Emactuzumab, a CSF1R Inhibitor, in Patients With Advanced Solid Tumors and Diffuse-Type Tenosynovial Giant Cell Tumor.
Journal: Clinical pharmacology and therapeutics
Published: April 08, 2020
First-in-Human Phase I Study of Single-agent Vanucizumab, A First-in-Class Bispecific Anti-Angiopoietin-2/Anti-VEGF-A Antibody, in Adult Patients with Advanced Solid Tumors.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research
Published: June 02, 2017
The pharmacokinetics and pharmacodynamics of danirixin (GSK1325756)--a selective CXCR2 antagonist --in healthy adult subjects.
Journal: BMC pharmacology & toxicology
Published: October 28, 2014
TRPV1 inhibition does not prevent cold dry air-elicited symptoms in non-allergic rhinitis.
Journal: International journal of clinical pharmacology and therapeutics
Published: January 30, 2014
Transient receptor potential vanilloid 1 (TRPV1) antagonism in patients with refractory chronic cough: a double-blind randomized controlled trial.
Journal: The Journal of allergy and clinical immunology
Published: September 21, 2013
The pharmacokinetics of conventional and bioenhanced tablet formulations of danirixin (GSK1325756) following oral administration in healthy, elderly, human volunteers.
Journal: European journal of drug metabolism and pharmacokinetics
Published: June 18, 2013
The effects of a TRPV1 antagonist, SB-705498, in the treatment of seasonal allergic rhinitis.
Journal: International journal of clinical pharmacology and therapeutics
Published: June 06, 2013
Inhibition of capsaicin-driven nasal hyper-reactivity by SB-705498, a TRPV1 antagonist.
Journal: British journal of clinical pharmacology
Published: December 18, 2012
Efficacy, safety and tolerability of GSK2190915, a 5-lipoxygenase activating protein inhibitor, in adults and adolescents with persistent asthma: a randomised dose-ranging study.
Journal: Respiratory research
Published: December 11, 2012
Showing 1-11 of 11
Last Updated: 09/26/2026