Khaled O. Mohamed

Kasr El Aini Street
Cairo, C 11562, Egypt

Last Updated: 09/26/2026

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Found 26 publications

Design, synthesis and biological screening of some diaryl acetamide derivatives as potential cytotoxic agents on HL-60(TB) cell line.

Design, synthesis and biological screening of some diaryl acetamide derivatives as potential cytotoxic agents on HL-60(TB) cell line.

Journal: Bioorganic chemistry

Published: July 31, 2025

Design, synthesis and characterization of novel pyridazin-3-one derivatives: in vitro vasorelaxant activity and in silico insights into eNOS modulation.

Design, synthesis and characterization of novel pyridazin-3-one derivatives: in vitro vasorelaxant activity and in silico insights into eNOS modulation.

Journal: RSC medicinal chemistry

Published: December 16, 2024

Discovery of novel octahydroquinazoline scaffolds endowed with dual inhibition of tubulin polymerization/Eg5 against HCC: Apoptotic and radio-chemotherapeutic studies.

Discovery of novel octahydroquinazoline scaffolds endowed with dual inhibition of tubulin polymerization/Eg5 against HCC: Apoptotic and radio-chemotherapeutic studies.

Journal: Bioorganic chemistry

Published: February 14, 2024

Pyroptosis and chemical classification of pyroptotic agents.

Pyroptosis and chemical classification of pyroptotic agents.

Journal: Molecular diversity

Published: January 21, 2024

Novel Pyrimidine-5-Carbonitriles as potential apoptotic and antiproliferative agents by dual inhibition of EGFRWT/T790M and PI3k enzymes; Design, Synthesis, biological Evaluation, and docking studies.

Novel Pyrimidine-5-Carbonitriles as potential apoptotic and antiproliferative agents by dual inhibition of EGFRWT/T790M and PI3k enzymes; Design, Synthesis, biological Evaluation, and docking studies.

Journal: Bioorganic chemistry

Published: December 31, 2023

Novel indolyl 1,2,4-triazole derivatives as potential anti-proliferative agents: in silico studies, synthesis, and biological evaluation.

Novel indolyl 1,2,4-triazole derivatives as potential anti-proliferative agents: in silico studies, synthesis, and biological evaluation.

Journal: RSC medicinal chemistry

Published: September 25, 2023

Synthesis of novel pyrimido[4,5-b]quinoline derivatives as dual EGFR/HER2 inhibitors as anticancer agents.

Synthesis of novel pyrimido[4,5-b]quinoline derivatives as dual EGFR/HER2 inhibitors as anticancer agents.

Journal: Archiv der Pharmazie

Published: September 16, 2023

Design, synthesis, and biological evaluation of new pyrimidine-5-carbonitrile derivatives as novel anti-cancer, dual EGFRWT/COX-2 inhibitors with docking studies.

Design, synthesis, and biological evaluation of new pyrimidine-5-carbonitrile derivatives as novel anti-cancer, dual EGFRWT/COX-2 inhibitors with docking studies.

Journal: RSC advances

Published: September 07, 2023

New Phenylthiazoles: Design, Synthesis, and Biological Evaluation as Antibacterial, Antifungal, and Anti-COVID-19 Candidates.

New Phenylthiazoles: Design, Synthesis, and Biological Evaluation as Antibacterial, Antifungal, and Anti-COVID-19 Candidates.

Journal: Chemistry & biodiversity

Published: August 01, 2023

Synthesis of novel pyrimido[4,5-b]quinolines as potential anticancer agents and HER2 inhibitors.

Synthesis of novel pyrimido[4,5-b]quinolines as potential anticancer agents and HER2 inhibitors.

Journal: Chemical biology & drug design

Published: May 12, 2023

The Anti-MRSA Activity of Phenylthiazoles: A Comprehensive Review.

The Anti-MRSA Activity of Phenylthiazoles: A Comprehensive Review.

Journal: Current pharmaceutical design

Published: May 07, 2022

Recent Modifications of Anti-dementia Agents Focusing on Tacrine and/or Donepezil Analogs.

Recent Modifications of Anti-dementia Agents Focusing on Tacrine and/or Donepezil Analogs.

Journal: Medicinal chemistry (Shariqah (United Arab Emirates))

Published: April 08, 2022

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Last Updated: 09/26/2026