Khrystyna Platko

St. Joseph's Hospital
Hamilton, ON, Canada

Last Updated: 09/26/2026

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Found 19 publications

GDF10 is a negative regulator of vascular calcification.

GDF10 is a negative regulator of vascular calcification.

Journal: The Journal of biological chemistry

Published: April 03, 2024

A Metabolic Enhancer Protects against Diet-Induced Obesity and Liver Steatosis and Corrects a Pro-Atherogenic Serum Profile in Mice.

A Metabolic Enhancer Protects against Diet-Induced Obesity and Liver Steatosis and Corrects a Pro-Atherogenic Serum Profile in Mice.

Journal: Nutrients

Published: April 10, 2023

The Emerging Roles of Intracellular PCSK9 and Their Implications in Endoplasmic Reticulum Stress and Metabolic Diseases.

The Emerging Roles of Intracellular PCSK9 and Their Implications in Endoplasmic Reticulum Stress and Metabolic Diseases.

Journal: Metabolites

Published: January 17, 2022

Inhibitory Antibodies against PCSK9 Reduce Surface CD36 and Mitigate Diet-Induced Renal Lipotoxicity.

Inhibitory Antibodies against PCSK9 Reduce Surface CD36 and Mitigate Diet-Induced Renal Lipotoxicity.

Journal: Kidney360

Published: November 02, 2021

Calcium as a reliable marker for the quantitative assessment of endoplasmic reticulum stress in live cells.

Calcium as a reliable marker for the quantitative assessment of endoplasmic reticulum stress in live cells.

Journal: The Journal of biological chemistry

Published: December 17, 2020

Caffeine blocks SREBP2-induced hepatic PCSK9 expression to enhance LDLR-mediated cholesterol clearance.

Caffeine blocks SREBP2-induced hepatic PCSK9 expression to enhance LDLR-mediated cholesterol clearance.

Journal: Nature communications

Published: August 17, 2020

TDAG51 (T-Cell Death-Associated Gene 51) Is a Key Modulator of Vascular Calcification and Osteogenic Transdifferentiation of Arterial Smooth Muscle Cells.

TDAG51 (T-Cell Death-Associated Gene 51) Is a Key Modulator of Vascular Calcification and Osteogenic Transdifferentiation of Arterial Smooth Muscle Cells.

Journal: Arteriosclerosis, thrombosis, and vascular biology

Published: May 22, 2020

Interstitial Cell Remodeling Promotes Aberrant Adipogenesis in Dystrophic Muscles.

Interstitial Cell Remodeling Promotes Aberrant Adipogenesis in Dystrophic Muscles.

Journal: Cell reports

Published: August 29, 2019

Pcsk9 knockout exacerbates diet-induced non-alcoholic steatohepatitis, fibrosis and liver injury in mice.

Pcsk9 knockout exacerbates diet-induced non-alcoholic steatohepatitis, fibrosis and liver injury in mice.

Journal: JHEP reports : innovation in hepatology

Published: April 13, 2019

GDF10 blocks hepatic PPARγ activation to protect against diet-induced liver injury.

GDF10 blocks hepatic PPARγ activation to protect against diet-induced liver injury.

Journal: Molecular metabolism

Published: April 09, 2019

The loss-of-function PCSK9Q152H variant increases ER chaperones GRP78 and GRP94 and protects against liver injury.

The loss-of-function PCSK9Q152H variant increases ER chaperones GRP78 and GRP94 and protects against liver injury.

Journal: The Journal of clinical investigation

Published: March 06, 2019

Diet-induced hepatic steatosis abrogates cell-surface LDLR by inducing de novo PCSK9 expression in mice.

Diet-induced hepatic steatosis abrogates cell-surface LDLR by inducing de novo PCSK9 expression in mice.

Journal: The Journal of biological chemistry

Published: February 19, 2019

Showing 1-12 of 19

Last Updated: 09/26/2026