Ki-young F. Lee
AB, Canada
Last Updated: 09/26/2026
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Found 36 publications
Elevated AMPKα2 expression driven by CITED2-dependent CBP/p300 mediated H3K27 acetylation confers doxorubicin resistance in triple-negative breast cancer stem cells.
Journal: International journal of biological macromolecules
Published: November 09, 2025
Lgmn targets two distinct GPCRs, PAR2 and µ-OR1, and induces cell death in acute lymphoblastic leukemia through an intracellular Ca²⁺ imbalance triggered by ER Ca²⁺ release.
Journal: Cell death discovery
Published: October 13, 2025
AMPKα2 attenuates doxorubicin induced ferroptosis by promoting NCOA4 degradation in triple negative breast cancer.
Journal: Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy
Published: August 27, 2025
In Ovo Xenografting of Patient-Derived Acute Lymphoblastic Leukemia (ALL) Cells (PDX-ALL).
Journal: Journal of visualized experiments : JoVE
Published: August 18, 2025
L-asparaginase is a PAR2 N-terminal protease that unmasks the PAR2 tethered ligand.
Journal: Cell death discovery
Published: February 06, 2025
L-asparaginase induces IP3R-mediated ER Ca2+ release by targeting µ-OR1 and PAR2 and kills acute lymphoblastic leukemia cells.
Journal: Cell death discovery
Published: April 05, 2024
PKA inhibition kills L-asparaginase-resistant leukemic cells from relapsed acute lymphoblastic leukemia patients.
Journal: Cell death discovery
Published: February 20, 2024
PKA inhibition is a central step in D,L-methadone-induced ER Ca2+ release and subsequent apoptosis in acute lymphoblastic leukemia.
Journal: Frontiers in cell and developmental biology
Published: February 20, 2024
Biochemical and biophysical characterization of the RAS family small GTPase protein DiRAS3.
Journal: Protein expression and purification
Published: July 25, 2023
Editorial: Biomarkers and therapeutic strategies in acute lymphoblastic leukemia.
Journal: Frontiers in cell and developmental biology
Published: April 24, 2023
Requirement for ER-mitochondria Ca2+ transfer, ROS production and mPTP formation in L-asparaginase-induced apoptosis of acute lymphoblastic leukemia cells.
Journal: Frontiers in cell and developmental biology
Published: December 14, 2022
2021 Canadian Surgery Forum: Virtual, online Sept. 21-24, 2021.
Journal: Canadian journal of surgery. Journal canadien de chirurgie
Published: April 28, 2022
Last Updated: 09/26/2026