Kilian M. Huber

Old Road Campus, Roosevelt Drive
Oxford, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 75 publications

Targeted Protein Degradation of NUDT5 Dissociates Catalytic Inhibition from Protein Loss in 6-Thioguanine Response.

Targeted Protein Degradation of NUDT5 Dissociates Catalytic Inhibition from Protein Loss in 6-Thioguanine Response.

Journal: Nature communications

Published: February 12, 2026

Multiomic profiling of responses to clinical and novel bisphosphonates reveals extraskeletal effects on ageing related signatures.

Multiomic profiling of responses to clinical and novel bisphosphonates reveals extraskeletal effects on ageing related signatures.

Journal: Signal transduction and targeted therapy

Published: November 09, 2025

A non-enzymatic role of Nudix hydrolase 5 in repressing purine de novo synthesis.

A non-enzymatic role of Nudix hydrolase 5 in repressing purine de novo synthesis.

Journal: Science (New York, N.Y.)

Published: November 06, 2025

Advances in BRET probes for intracellular target engagement studies.

Advances in BRET probes for intracellular target engagement studies.

Journal: Nature chemical biology

Published: May 05, 2025

Bisphosphonates Trigger Anti-Ageing Effects Across Multiple Cell Types and Protect Against Senescence.

Bisphosphonates Trigger Anti-Ageing Effects Across Multiple Cell Types and Protect Against Senescence.

Journal: bioRxiv : the preprint server for biology

Published: April 08, 2025

Drug repurposing in amyotrophic lateral sclerosis (ALS).

Drug repurposing in amyotrophic lateral sclerosis (ALS).

Journal: Expert opinion on drug discovery

Published: March 03, 2025

A BRET biosensor for measuring uncompetitive engagement of PRMT5 complexes in cells.

A BRET biosensor for measuring uncompetitive engagement of PRMT5 complexes in cells.

Journal: Nature communications

Published: February 14, 2025

Covalent Inhibitors of KEAP1 with Exquisite Selectivity.

Covalent Inhibitors of KEAP1 with Exquisite Selectivity.

Journal: Journal of medicinal chemistry

Published: November 21, 2024

Phenomics-Based Discovery of Novel Orthosteric Choline Kinase Inhibitors.

Phenomics-Based Discovery of Novel Orthosteric Choline Kinase Inhibitors.

Journal: Angewandte Chemie (International ed. in English)

Published: October 18, 2024

Toward target 2035: EUbOPEN - a public-private partnership to enable & unlock biology in the open.

Toward target 2035: EUbOPEN - a public-private partnership to enable & unlock biology in the open.

Journal: RSC medicinal chemistry

Published: September 18, 2024

Discovery of potent SARS-CoV-2 nsp3 macrodomain inhibitors uncovers lack of translation to cellular antiviral response.

Discovery of potent SARS-CoV-2 nsp3 macrodomain inhibitors uncovers lack of translation to cellular antiviral response.

Journal: bioRxiv : the preprint server for biology

Published: September 04, 2024

Paralogue-Selective Degradation of the Lysine Acetyltransferase EP300.

Paralogue-Selective Degradation of the Lysine Acetyltransferase EP300.

Journal: JACS Au

Published: May 16, 2024

Showing 1-12 of 75

Last Updated: 09/26/2026