Last Updated: 09/26/2026
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Found 169 publications
Pediatric sarcomas: challenges and opportunities.
Journal: Genes & development
Published: August 04, 2026
Splicing-associated network PAK1-CLK1/4-SRRM1 is a vulnerability to overcome chemoresistance in human and mouse acute myeloid leukemia.
Journal: Science translational medicine
Published: July 08, 2026
Evaluation of HDAC8 as a Druggable Target in STAG2-Mutant Ewing Sarcoma.
Journal: ACS chemical biology
Published: April 08, 2026
An epigenetic bifunctional that toggles between transactivation and repression.
Journal: bioRxiv : the preprint server for biology
Published: March 27, 2026
Tabular foundation model predicts alternative lengthening of telomeres (ALT) and identifies SMARCAL1 as a target in ALT-driven cancers.
Journal: bioRxiv : the preprint server for biology
Published: March 18, 2026
A first-in-pediatric study of ALRN-6924, a novel stapled-peptide dual MDM2/MDMX inhibitor, for children with advanced hematologic and solid malignancies.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research
Published: February 17, 2026
A First-in-Pediatric Study of ALRN-6924, a Novel Stapled-Peptide Dual MDM2/MDMX Inhibitor, for Children with Advanced Hematologic and Solid Malignancies.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research
Published: February 17, 2026
Inhibition of USP7 Destabilizes the Noncanonical PRC1.1 Complex and Induces Neuroblastoma Differentiation.
Journal: Molecular cancer research : MCR
Published: October 22, 2025
CDK8 Inhibition Releases the Muscle Differentiation Block in Fusion-driven Alveolar Rhabdomyosarcoma.
Journal: bioRxiv : the preprint server for biology
Published: August 12, 2025
Chromatin Perturbation Promotes Susceptibility to Hypomethylating Agents.
Journal: bioRxiv : the preprint server for biology
Published: August 06, 2025
Last Updated: 09/26/2026