Kirsty E. Waddington

London, ENG WC1E6JF, United Kingdom

Last Updated: 09/26/2026

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Found 18 publications

Patients with multiple sclerosis who develop immunogenicity to interferon-beta have distinct transcriptomic and proteomic signatures prior to treatment which are associated with disease severity.

Patients with multiple sclerosis who develop immunogenicity to interferon-beta have distinct transcriptomic and proteomic signatures prior to treatment which are associated with disease severity.

Journal: Clinical immunology (Orlando, Fla.)

Published: May 22, 2024

Dysregulated lipid metabolism networks modulate T-cell function in people with relapsing-remitting multiple sclerosis.

Dysregulated lipid metabolism networks modulate T-cell function in people with relapsing-remitting multiple sclerosis.

Journal: Clinical and experimental immunology

Published: October 05, 2023

Blood metabolomic and transcriptomic signatures stratify patient subgroups in multiple sclerosis according to disease severity.

Blood metabolomic and transcriptomic signatures stratify patient subgroups in multiple sclerosis according to disease severity.

Journal: iScience

Published: September 19, 2023

LXR directly regulates glycosphingolipid synthesis and affects human CD4+ T cell function.

LXR directly regulates glycosphingolipid synthesis and affects human CD4+ T cell function.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: May 19, 2021

Serum Metabolomic Signatures Can Predict Subclinical Atherosclerosis in Patients With Systemic Lupus Erythematosus.

Serum Metabolomic Signatures Can Predict Subclinical Atherosclerosis in Patients With Systemic Lupus Erythematosus.

Journal: Arteriosclerosis, thrombosis, and vascular biology

Published: February 04, 2021

Disrupted Lipid Metabolism in Multiple Sclerosis: A Role for Liver X Receptors?

Disrupted Lipid Metabolism in Multiple Sclerosis: A Role for Liver X Receptors?

Journal: Frontiers in endocrinology

Published: December 09, 2020

Increased apolipoprotein-B:A1 ratio predicts cardiometabolic risk in patients with juvenile onset SLE.

Increased apolipoprotein-B:A1 ratio predicts cardiometabolic risk in patients with juvenile onset SLE.

Journal: EBioMedicine

Published: November 17, 2020

Stratification of Patients With Sjögren's Syndrome and Patients With Systemic Lupus Erythematosus According to Two Shared Immune Cell Signatures, With Potential Therapeutic Implications.

Stratification of Patients With Sjögren's Syndrome and Patients With Systemic Lupus Erythematosus According to Two Shared Immune Cell Signatures, With Potential Therapeutic Implications.

Journal: Arthritis & rheumatology (Hoboken, N.J.)

Published: October 02, 2020

COVID-19-associated hyperinflammation and escalation of patient care: a retrospective longitudinal cohort study.

COVID-19-associated hyperinflammation and escalation of patient care: a retrospective longitudinal cohort study.

Journal: The Lancet. Rheumatology

Published: August 31, 2020

Using Serum Metabolomics to Predict Development of Anti-drug Antibodies in Multiple Sclerosis Patients Treated With IFNβ.

Using Serum Metabolomics to Predict Development of Anti-drug Antibodies in Multiple Sclerosis Patients Treated With IFNβ.

Journal: Frontiers in immunology

Published: March 20, 2020

Analyzing T-Cell Plasma Membrane Lipids by Flow Cytometry.

Analyzing T-Cell Plasma Membrane Lipids by Flow Cytometry.

Journal: Methods in molecular biology (Clifton, N.J.)

Published: March 03, 2019

Modulating PCAF/GCN5 Immune Cell Function through a PROTAC Approach.

Modulating PCAF/GCN5 Immune Cell Function through a PROTAC Approach.

Journal: ACS chemical biology

Published: September 12, 2018

Showing 1-12 of 18

Last Updated: 09/26/2026