Klas G. Wiman

Stockholm, AB, Sweden

Last Updated: 09/26/2026

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Found 55 publications

Mice carrying nonsense mutant p53 develop frequent multicentric or metastatic tumors.

Mice carrying nonsense mutant p53 develop frequent multicentric or metastatic tumors.

Journal: Cell death & disease

Published: September 03, 2025

Capturing Unicorns: Targeting Cancers With TP53 Mutations, RAS Alterations Beyond G12C, and MTAP Loss-No Target Is Out of the Realm of Possibility.

Capturing Unicorns: Targeting Cancers With TP53 Mutations, RAS Alterations Beyond G12C, and MTAP Loss-No Target Is Out of the Realm of Possibility.

Journal: American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting

Published: May 28, 2025

Therapeutic targeting of TP53 nonsense mutations in cancer.

Therapeutic targeting of TP53 nonsense mutations in cancer.

Journal: Upsala journal of medical sciences

Published: April 20, 2024

Proteome-wide CETSA reveals diverse apoptosis-inducing mechanisms converging on an initial apoptosis effector stage at the nuclear periphery.

Proteome-wide CETSA reveals diverse apoptosis-inducing mechanisms converging on an initial apoptosis effector stage at the nuclear periphery.

Journal: Cell reports

Published: February 22, 2024

Pharmacological reactivation of p53 in the era of precision anticancer medicine.

Pharmacological reactivation of p53 in the era of precision anticancer medicine.

Journal: Nature reviews. Clinical oncology

Published: November 23, 2023

Novel compounds that synergize with aminoglycoside G418 or eRF3 degraders for translational readthrough of nonsense mutant TP53 and PTEN.

Novel compounds that synergize with aminoglycoside G418 or eRF3 degraders for translational readthrough of nonsense mutant TP53 and PTEN.

Journal: RNA biology

Published: June 20, 2023

Correction to: Wig-1 regulates cell cycle arrest and cell death through the p53 targets FAS and 14-3-3s.

Correction to: Wig-1 regulates cell cycle arrest and cell death through the p53 targets FAS and 14-3-3s.

Journal: Oncogene

Published: January 27, 2023

Pharmacological induction of translational readthrough of nonsense mutations in the retinoblastoma (RB1) gene.

Pharmacological induction of translational readthrough of nonsense mutations in the retinoblastoma (RB1) gene.

Journal: PloS one

Published: January 23, 2023

Correction: Mutant p53-reactivating compound APR-246 synergizes with asparaginase in inducing growth suppression in acute lymphoblastic leukemia cells.

Correction: Mutant p53-reactivating compound APR-246 synergizes with asparaginase in inducing growth suppression in acute lymphoblastic leukemia cells.

Journal: Cell death & disease

Published: August 03, 2022

Translational readthrough of nonsense mutant TP53 by mRNA incorporation of 5-Fluorouridine.

Translational readthrough of nonsense mutant TP53 by mRNA incorporation of 5-Fluorouridine.

Journal: Cell death & disease

Published: May 24, 2022

Evolutionary history of the p53 family DNA-binding domain: insights from an Alvinella pompejana homolog.

Evolutionary history of the p53 family DNA-binding domain: insights from an Alvinella pompejana homolog.

Journal: Cell death & disease

Published: December 02, 2021

Mutant p53-reactivating compound APR-246 synergizes with asparaginase in inducing growth suppression in acute lymphoblastic leukemia cells.

Mutant p53-reactivating compound APR-246 synergizes with asparaginase in inducing growth suppression in acute lymphoblastic leukemia cells.

Journal: Cell death & disease

Published: May 06, 2021

Showing 1-12 of 55

Last Updated: 09/26/2026