Klaus Dinkel
Dortmund, NW, Germany
Last Updated: 09/26/2026
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Found 14 publications
An Imidazo[2,1-b][1,3,4]thiadiazole Derivative Inhibits the Virulence Factor α-Hemolysin by Blocking the Pullout of Its Stem Domain.
Journal: ChemMedChem
Published: December 08, 2025
Correction: The P2X7R-antagonist AFC-5128 ameliorates chronic experimental autoimmune encephalomyelitis in a preventive and therapeutic paradigm.
Journal: Frontiers in immunology
Published: June 23, 2025
The P2X7R-antagonist AFC-5128 ameliorates chronic experimental autoimmune encephalomyelitis in a preventive and therapeutic paradigm.
Journal: Frontiers in immunology
Published: January 03, 2025
Highly potent quinoxalinediones inhibit α-hemolysin and ameliorate Staphylococcus aureus lung infections.
Journal: Cell host & microbe
Published: August 23, 2024
P2X7 receptor antagonism suppresses epileptiform-like activity in an inflammation-primed human iPSC-derived neuron model of drug-resistant epilepsy.
Journal: British journal of pharmacology
Published: August 21, 2024
TRPC5 controls the adrenaline-mediated counter regulation of hypoglycemia.
Journal: The EMBO journal
Published: June 14, 2024
Functional expression of the ATP-gated P2X7 receptor in human iPSC-derived astrocytes.
Journal: Purinergic signalling
Published: March 25, 2023
Increased expression of the ATP-gated P2X7 receptor reduces responsiveness to anti-convulsants during status epilepticus in mice.
Journal: British journal of pharmacology
Published: August 28, 2021
Chronic high dose P2X7 receptor inhibition exacerbates cancer-induced bone pain.
Journal: European journal of pharmacology
Published: July 03, 2018
TRPC4/TRPC5 channels mediate adverse reaction to the cancer cell cytotoxic agent (-)-Englerin A.
Journal: Oncotarget
Published: September 29, 2017
Identification of an (-)-englerin A analogue, which antagonizes (-)-englerin A at TRPC1/4/5 channels.
Journal: British journal of pharmacology
Published: June 12, 2017
Last Updated: 09/26/2026