Klaus Schiene
Aachen, NW 52078, Germany
Last Updated: 09/26/2026
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Found 16 publications
Inhibition of experimental visceral pain in rodents by cebranopadol.
Journal: Behavioural pharmacology
Published: August 31, 2018
Investigation of TRPV1 loss-of-function phenotypes in TRPV1 Leu206Stop mice generated by N-ethyl-N-nitrosourea mutagenesis.
Journal: Biochemical and biophysical research communications
Published: April 04, 2018
Nociceptin/orphanin FQ opioid peptide (NOP) receptor and µ-opioid peptide (MOP) receptors both contribute to the anti-hypersensitive effect of cebranopadol in a rat model of arthritic pain.
Journal: European journal of pharmacology
Published: December 12, 2017
Electrophysiological characterization of activation state-dependent Ca(v)2 channel antagonist TROX-1 in spinal nerve injured rats.
Journal: Neuroscience
Published: January 19, 2015
Pyridine C-region analogs of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides as potent TRPV1 antagonists.
Journal: European journal of medicinal chemistry
Published: December 03, 2014
6,6-Fused heterocyclic ureas as highly potent TRPV1 antagonists.
Journal: Bioorganic & medicinal chemistry letters
Published: December 03, 2014
Mechanical hyperalgesia in rats with diabetic polyneuropathy is selectively inhibited by local peripheral nociceptin/orphanin FQ receptor and µ-opioid receptor agonism.
Journal: European journal of pharmacology
Published: June 12, 2014
2-Alkyl/alkenyl substituted pyridine C-region analogues of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides as highly potent TRPV1 antagonists.
Journal: Bioorganic & medicinal chemistry letters
Published: April 18, 2014
Cebranopadol: a novel potent analgesic nociceptin/orphanin FQ peptide and opioid receptor agonist.
Journal: The Journal of pharmacology and experimental therapeutics
Published: April 10, 2014
Pharmacogenomic study of the role of the nociceptin/orphanin FQ receptor and opioid receptors in diabetic hyperalgesia.
Journal: European journal of pharmacology
Published: March 13, 2014
TRPV1 antagonist with high analgesic efficacy: 2-Thio pyridine C-region analogues of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides.
Journal: Bioorganic & medicinal chemistry
Published: July 22, 2013
Burrowing as a non-reflex behavioural readout for analgesic action in a rat model of sub-chronic knee joint inflammation.
Journal: European journal of pain (London, England)
Published: May 31, 2013
Last Updated: 09/26/2026