Ko Kumura
Yokohama, Japan
Last Updated: 09/26/2026
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Found 12 publications
ME3183, a novel phosphodiesterase-4 inhibitor, exhibits potent anti-inflammatory effects and is well tolerated in a non-clinical study.
Journal: European journal of pharmacology
Published: May 30, 2023
Characterization of compound A, a novel lincomycin derivative active against methicillin-resistant Staphylococcus aureus.
Journal: The Journal of antibiotics
Published: July 22, 2020
Synthesis and antibacterial activity of novel lincomycin derivatives. IV. Optimization of an N-6 substituent.
Journal: The Journal of antibiotics
Published: August 22, 2017
Synthesis and SARs of novel lincomycin derivatives Part 5: optimization of lincomycin analogs exhibiting potent antibacterial activities by chemical modification at the 6- and 7-positions.
Journal: The Journal of antibiotics
Published: May 20, 2017
Synthesis and antibacterial activity of novel lincomycin derivatives. III. Optimization of a phenyl thiadiazole moiety.
Journal: The Journal of antibiotics
Published: February 19, 2017
Synthesis and structure-activity relationships of novel lincomycin derivatives. Part 4: synthesis of novel lincomycin analogs modified at the 6- and 7-positions and their potent antibacterial activities.
Journal: The Journal of antibiotics
Published: January 18, 2017
Synthesis and antibacterial activity of novel lincomycin derivatives. II. Exploring (7S)-7-(5-aryl-1,3,4-thiadiazol-2-yl-thio)-7-deoxylincomycin derivatives.
Journal: The Journal of antibiotics
Published: August 11, 2016
Synthesis and structure-activity relationships of novel lincomycin derivatives part 3: discovery of the 4-(pyrimidin-5-yl)phenyl group in synthesis of 7(S)-thiolincomycin analogs.
Journal: The Journal of antibiotics
Published: June 28, 2016
Synthesis and structure-activity relationships of novel lincomycin derivatives. Part 2. Synthesis of 7(S)-7-deoxy-7-(4-morpholinocarbonylphenylthio)lincomycin and its 3-dimensional analysis with rRNA.
Journal: The Journal of antibiotics
Published: October 10, 2015
Synthesis and antibacterial activity of novel lincomycin derivatives. I. Enhancement of antibacterial activities by introduction of substituted azetidines.
Journal: The Journal of antibiotics
Published: August 18, 2015
Synthesis and structure-activity relationships of novel lincomycin derivatives. Part 1. Newly generated antibacterial activities against Gram-positive bacteria with erm gene by C-7 modification.
Journal: The Journal of antibiotics
Published: August 04, 2015
Synthesis of novel lincomycin derivatives and their in vitro antibacterial activities.
Journal: The Journal of antibiotics
Published: December 13, 2012
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Last Updated: 09/26/2026