Koen D. Flach
Amsterdam, NH 1066CX, Netherlands
Last Updated: 09/26/2026
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Found 15 publications
Cohesin-mediated loop extrusion and enhancer-associated factors additively contribute to Sox2 looping with its distal enhancer.
Journal: Genes & development
Published: August 25, 2025
Distinct roles for CKM-Mediator in controlling Polycomb-dependent chromosomal interactions and priming genes for induction.
Journal: Nature structural & molecular biology
Published: November 12, 2021
A Mediator-cohesin axis controls heterochromatin domain formation.
Journal: Nature communications
Published: March 17, 2021
Perturbations in 3D genome organization can promote acquired drug resistance.
Journal: Cell reports
Published: February 18, 2021
A CRISPR-Cas9 screen identifies essential CTCF anchor sites for estrogen receptor-driven breast cancer cell proliferation.
Journal: Nucleic acids research
Published: January 29, 2019
Dissecting the predictive value of MAPK/AKT/estrogen-receptor phosphorylation axis in primary breast cancer to treatment response for tamoxifen over exemestane: a Translational Report of the Intergroup Exemestane Study (IES)-PathIES.
Journal: Breast cancer research and treatment
Published: October 03, 2018
The first decade of estrogen receptor cistromics in breast cancer.
Journal: The Journal of endocrinology
Published: February 11, 2016
SRC3 Phosphorylation at Serine 543 Is a Positive Independent Prognostic Factor in ER-Positive Breast Cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research
Published: December 21, 2014
Co-regulated gene expression by oestrogen receptor α and liver receptor homolog-1 is a feature of the oestrogen response in breast cancer cells.
Journal: Nucleic acids research
Published: September 20, 2013
Last Updated: 09/26/2026