Koji Umezawa

Nagano, Japan

Last Updated: 09/26/2026

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Found 36 publications

Backbone Steric Constraints Underlie High Passive Membrane Permeability of N-Alkyl Peptides.

Backbone Steric Constraints Underlie High Passive Membrane Permeability of N-Alkyl Peptides.

Journal: Angewandte Chemie (International ed. in English)

Published: March 07, 2026

Alkyl shikimates promote proliferation of human dermal fibroblasts and exhibit structure-activity relationships.

Alkyl shikimates promote proliferation of human dermal fibroblasts and exhibit structure-activity relationships.

Journal: Scientific reports

Published: February 11, 2026

Correlation between tight binding of inhibitors and their target selectivity toward the non-native state in the DYRK family of kinases.

Correlation between tight binding of inhibitors and their target selectivity toward the non-native state in the DYRK family of kinases.

Journal: Bioorganic & medicinal chemistry letters

Published: October 09, 2025

Bottom-up design of peptide shapes in water using oligomers of N-methyl-l/d-alanine.

Bottom-up design of peptide shapes in water using oligomers of N-methyl-l/d-alanine.

Journal: Chemical science

Published: February 25, 2025

Temperature vaulting: A method for screening of slow- and tight-binding inhibitors that selectively target kinases in their non-native state.

Temperature vaulting: A method for screening of slow- and tight-binding inhibitors that selectively target kinases in their non-native state.

Journal: European journal of medicinal chemistry

Published: February 16, 2025

Osteogenic CpG Oligodeoxynucleotide, iSN40, Inhibits Osteoclastogenesis in a TLR9-Dependent Manner.

Osteogenic CpG Oligodeoxynucleotide, iSN40, Inhibits Osteoclastogenesis in a TLR9-Dependent Manner.

Journal: Life (Basel, Switzerland)

Published: October 26, 2024

Development of the 12-Base Short Dimeric Myogenetic Oligodeoxynucleotide That Induces Myogenic Differentiation.

Development of the 12-Base Short Dimeric Myogenetic Oligodeoxynucleotide That Induces Myogenic Differentiation.

Journal: Biotech (Basel (Switzerland))

Published: March 17, 2024

A high-resolution structural characterization and physicochemical study of how a peptoid binds to an oncoprotein MDM2.

A high-resolution structural characterization and physicochemical study of how a peptoid binds to an oncoprotein MDM2.

Journal: Chemical science

Published: March 05, 2024

DnaK promotes autophosphorylation of DYRK1A and its family kinases in Escherichia coli-based cell-free protein expression.

DnaK promotes autophosphorylation of DYRK1A and its family kinases in Escherichia coli-based cell-free protein expression.

Journal: Biochemical and biophysical research communications

Published: October 23, 2023

Crystal structure and activity of a de novo enzyme, ferric enterobactin esterase Syn-F4.

Crystal structure and activity of a de novo enzyme, ferric enterobactin esterase Syn-F4.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: September 11, 2023

Myogenetic Oligodeoxynucleotide Induces Myocardial Differentiation of Murine Pluripotent Stem Cells.

Myogenetic Oligodeoxynucleotide Induces Myocardial Differentiation of Murine Pluripotent Stem Cells.

Journal: International journal of molecular sciences

Published: August 05, 2023

Genistein enhances NAD+ biosynthesis by upregulating nicotinamide phosphoribosyltransferase in adipocytes.

Genistein enhances NAD+ biosynthesis by upregulating nicotinamide phosphoribosyltransferase in adipocytes.

Journal: The Journal of nutritional biochemistry

Published: July 02, 2023

Showing 1-12 of 36

Last Updated: 09/26/2026