Kok O. Lee

Singapore, Singapore

Last Updated: 09/26/2026

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Found 31 publications

Metformin treatment is associated with an increase in bone mineral density in type 2 diabetes mellitus patients in China: A retrospective single center study.

Metformin treatment is associated with an increase in bone mineral density in type 2 diabetes mellitus patients in China: A retrospective single center study.

Journal: Diabetes & metabolism

Published: January 25, 2022

First use of gene therapy to treat growth hormone resistant dwarfism in a mouse model.

First use of gene therapy to treat growth hormone resistant dwarfism in a mouse model.

Journal: Gene therapy

Published: September 10, 2021

Charting the next century of insulin replacement with cell and gene therapies.

Charting the next century of insulin replacement with cell and gene therapies.

Journal: Med (New York, N.Y.)

Published: July 06, 2021

Association of decreased sperm motility and increased seminal plasma IGF-I, IGF-II, IGFBP-2, and PSA levels in infertile men.

Association of decreased sperm motility and increased seminal plasma IGF-I, IGF-II, IGFBP-2, and PSA levels in infertile men.

Journal: Endocrine

Published: May 06, 2021

Progressive endoplasmic reticulum stress over time due to human insulin gene mutation contributes to pancreatic beta cell dysfunction.

Progressive endoplasmic reticulum stress over time due to human insulin gene mutation contributes to pancreatic beta cell dysfunction.

Journal: Diabetologia

Published: December 11, 2020

Modification of a Constitutive to Glucose-Responsive Liver-Specific Promoter Resulted in Increased Efficacy of Adeno-Associated Virus Serotype 8-Insulin Gene Therapy of Diabetic Mice.

Modification of a Constitutive to Glucose-Responsive Liver-Specific Promoter Resulted in Increased Efficacy of Adeno-Associated Virus Serotype 8-Insulin Gene Therapy of Diabetic Mice.

Journal: Cells

Published: September 17, 2020

Contributions of Fasting and Postprandial Glucose Concentrations to Haemoglobin A1c in Drug-Naïve Mal-Glucose Metabolism in Chinese Population Using Continuous Glucose Monitoring System.

Contributions of Fasting and Postprandial Glucose Concentrations to Haemoglobin A1c in Drug-Naïve Mal-Glucose Metabolism in Chinese Population Using Continuous Glucose Monitoring System.

Journal: International journal of endocrinology

Published: August 27, 2019

New insights into human beta cell biology using human pluripotent stem cells.

New insights into human beta cell biology using human pluripotent stem cells.

Journal: Seminars in cell & developmental biology

Published: June 04, 2019

Efficacy and safety of pulsed intravenous methylprednisolone in early active thyroid eye disease.

Efficacy and safety of pulsed intravenous methylprednisolone in early active thyroid eye disease.

Journal: Orbit (Amsterdam, Netherlands)

Published: December 13, 2018

Development of a liver-specific Tet-off AAV8 vector for improved safety of insulin gene therapy for diabetes.

Development of a liver-specific Tet-off AAV8 vector for improved safety of insulin gene therapy for diabetes.

Journal: The journal of gene medicine

Published: September 11, 2018

Immunosuppression overcomes insulin- and vector-specific immune responses that limit efficacy of AAV2/8-mediated insulin gene therapy in NOD mice.

Immunosuppression overcomes insulin- and vector-specific immune responses that limit efficacy of AAV2/8-mediated insulin gene therapy in NOD mice.

Journal: Gene therapy

Published: August 06, 2018

Relationship between Thyroid Function and Kidney Function in Patients with Type 2 Diabetes.

Relationship between Thyroid Function and Kidney Function in Patients with Type 2 Diabetes.

Journal: International journal of endocrinology

Published: June 18, 2018

Showing 1-12 of 31

Last Updated: 09/26/2026