Kris Nys

Mechelen-bovelingen, VLG 2800, Belgium

Last Updated: 09/26/2026

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Found 15 publications

Discovery of GLPG4471, a potent and selective IRAK4 inhibitor for the treatment of inflammatory and autoimmune diseases.

Discovery of GLPG4471, a potent and selective IRAK4 inhibitor for the treatment of inflammatory and autoimmune diseases.

Journal: Bioorganic & medicinal chemistry letters

Published: June 27, 2025

Plasma cells are not restricted to the CD27+ phenotype: characterization of CD27-CD43+ antibody-secreting cells.

Plasma cells are not restricted to the CD27+ phenotype: characterization of CD27-CD43+ antibody-secreting cells.

Journal: Frontiers in immunology

Published: February 14, 2023

Sustained SREBP-1-dependent lipogenesis as a key mediator of resistance to BRAF-targeted therapy.

Sustained SREBP-1-dependent lipogenesis as a key mediator of resistance to BRAF-targeted therapy.

Journal: Nature communications

Published: July 27, 2017

Biopsy-derived Intestinal Epithelial Cell Cultures for Pathway-based Stratification of Patients With Inflammatory Bowel Disease.

Biopsy-derived Intestinal Epithelial Cell Cultures for Pathway-based Stratification of Patients With Inflammatory Bowel Disease.

Journal: Journal of Crohn's & colitis

Published: March 24, 2017

Therapeutic innovations in inflammatory bowel diseases.

Therapeutic innovations in inflammatory bowel diseases.

Journal: Clinical pharmacology and therapeutics

Published: September 24, 2015

Strong Upregulation of AIM2 and IFI16 Inflammasomes in the Mucosa of Patients with Active Inflammatory Bowel Disease.

Strong Upregulation of AIM2 and IFI16 Inflammasomes in the Mucosa of Patients with Active Inflammatory Bowel Disease.

Journal: Inflammatory bowel diseases

Published: August 28, 2015

ATG16L1: A multifunctional susceptibility factor in Crohn disease.

ATG16L1: A multifunctional susceptibility factor in Crohn disease.

Journal: Autophagy

Published: April 24, 2015

Impact of T300A Variant of ATG16L1 on Antibacterial Response, Risk of Culture Positive Infections, and Clinical Course of Crohn's Disease.

Impact of T300A Variant of ATG16L1 on Antibacterial Response, Risk of Culture Positive Infections, and Clinical Course of Crohn's Disease.

Journal: Clinical and translational gastroenterology

Published: March 09, 2015

Genetic association and functional role of Crohn disease risk alleles involved in microbial sensing, autophagy, and endoplasmic reticulum (ER) stress.

Genetic association and functional role of Crohn disease risk alleles involved in microbial sensing, autophagy, and endoplasmic reticulum (ER) stress.

Journal: Autophagy

Published: November 20, 2013

BNIP3 supports melanoma cell migration and vasculogenic mimicry by orchestrating the actin cytoskeleton.

BNIP3 supports melanoma cell migration and vasculogenic mimicry by orchestrating the actin cytoskeleton.

Journal: Cell death & disease

Published: October 30, 2013

Autophagy: a new target or an old strategy for the treatment of Crohn's disease?

Autophagy: a new target or an old strategy for the treatment of Crohn's disease?

Journal: Nature reviews. Gastroenterology & hepatology

Published: April 18, 2013

Tumor vessel normalization by chloroquine independent of autophagy.

Tumor vessel normalization by chloroquine independent of autophagy.

Journal: Cancer cell

Published: December 19, 2012

Showing 1-12 of 15

Last Updated: 09/26/2026