Krishan G. Thakur

Chandigarh, CH, India

Last Updated: 09/26/2026

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Found 59 publications

Targeting Metallo-β-Lactamases: Discovery of Novel Dihydro-Chromeno Pyrrole (dCPs) Derivatives for Combating Drug-Resistant Infections.

Targeting Metallo-β-Lactamases: Discovery of Novel Dihydro-Chromeno Pyrrole (dCPs) Derivatives for Combating Drug-Resistant Infections.

Journal: Journal of medicinal chemistry
Published: June 15, 2026

Development of Benzimidazole-Based BZ-30 as an Orally Bioavailable Broad-Spectrum Inhibitor of SARS-CoV-2.

Development of Benzimidazole-Based BZ-30 as an Orally Bioavailable Broad-Spectrum Inhibitor of SARS-CoV-2.

Journal: Journal of medicinal chemistry
Published: April 13, 2026

Structural and functional characterization of VapBC52 toxin-antitoxin system from Mycobacterium tuberculosis.

Structural and functional characterization of VapBC52 toxin-antitoxin system from Mycobacterium tuberculosis.

Journal: Nucleic acids research
Published: January 29, 2026

Structural and biophysical insights into RomR, MglB, and MglC interactions involved in regulating cell polarity in Myxococcus xanthus.

Structural and biophysical insights into RomR, MglB, and MglC interactions involved in regulating cell polarity in Myxococcus xanthus.

Journal: The Journal of biological chemistry
Published: October 22, 2025

Targeted screening and rational optimization of bazedoxifene analogs as pan-variant SARS-CoV-2 entry inhibitors with improved pharmacokinetics.

Targeted screening and rational optimization of bazedoxifene analogs as pan-variant SARS-CoV-2 entry inhibitors with improved pharmacokinetics.

Journal: European journal of medicinal chemistry
Published: September 28, 2025

The yxiD gene from Bacillus subtilis 6633 encodes a polymorphic toxin with tRNase activity and is neutralized by the cognate immunity protein YxxD.

The yxiD gene from Bacillus subtilis 6633 encodes a polymorphic toxin with tRNase activity and is neutralized by the cognate immunity protein YxxD.

Journal: Nucleic acids research
Published: June 04, 2025

The role of amino acid composition in the antibacterial activity of laterosporulin analogs.

The role of amino acid composition in the antibacterial activity of laterosporulin analogs.

Journal: Journal of applied microbiology
Published: June 03, 2025

Strategic Design and Optimization of Umifenovir Analogues: Balancing Antiviral Efficacy and hERG Toxicity against SARS-CoV-2.

Strategic Design and Optimization of Umifenovir Analogues: Balancing Antiviral Efficacy and hERG Toxicity against SARS-CoV-2.

Journal: Journal of medicinal chemistry
Published: April 23, 2025

Discovery of Conformationally Constrained Dihydro Benzo-Indole Derivatives as Metallo-β-Lactamase Inhibitors to Tackle Multidrug-Resistant Bacterial Infections.

Discovery of Conformationally Constrained Dihydro Benzo-Indole Derivatives as Metallo-β-Lactamase Inhibitors to Tackle Multidrug-Resistant Bacterial Infections.

Journal: Journal of medicinal chemistry
Published: March 26, 2025

9-fluorenone-based synthetic sulfonamide compounds as dual inhibitors of SARS-CoV-2 Main-Protease and Papain-like Protease.

9-fluorenone-based synthetic sulfonamide compounds as dual inhibitors of SARS-CoV-2 Main-Protease and Papain-like Protease.

Journal: Molecular diversity
Published: March 03, 2025

Spike conformational and glycan heterogeneity associated with furin cleavage causes incomplete neutralization of SARS-CoV-2.

Spike conformational and glycan heterogeneity associated with furin cleavage causes incomplete neutralization of SARS-CoV-2.

Journal: Nature communications
Published: March 01, 2025

Identification and Characterization of a Novel Protein-Protein Interaction Among SARS-CoV-2 Nucleocapsid, Host SFPQ, and hnRNP U and Its Potential Role in Virus Replication.

Identification and Characterization of a Novel Protein-Protein Interaction Among SARS-CoV-2 Nucleocapsid, Host SFPQ, and hnRNP U and Its Potential Role in Virus Replication.

Journal: Biology of the cell
Published: February 24, 2025
Showing 1-12 of 59

Last Updated: 09/26/2026