Last Updated: 09/26/2026
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Found 16 publications
Translational and clinical development of therapeutic siRNA and ASOs: current industry practices, perspectives, and recommendations.
Journal: Nucleic acids research
Published: March 03, 2025
Pharmacokinetics of nano- and microcrystal formulations of low solubility compounds after intramuscular injection to mice.
Journal: The Journal of pharmacy and pharmacology
Published: March 05, 2024
Aminobenzotriazole inhibits and induces several key drug metabolizing enzymes complicating its utility as a pan CYP inhibitor for reaction phenotyping.
Journal: Clinical and translational science
Published: November 09, 2023
Quantitative evaluation of trastuzumab deruxtecan pharmacokinetics and pharmacodynamics in mouse models of varying degrees of HER2 expression.
Journal: CPT: pharmacometrics & systems pharmacology
Published: October 12, 2023
Pharmacokinetic evaluation of poorly soluble compounds formulated as nano- or microcrystals after intraperitoneal injection to mice.
Journal: International journal of pharmaceutics
Published: November 08, 2022
Small circular interfering RNAs (sciRNAs) as a potent therapeutic platform for gene-silencing.
Journal: Nucleic acids research
Published: July 06, 2021
Cyclic Thiosulfinates as a Novel Class of Disulfide Cleavable Cross-Linkers for Rapid Hydrogel Synthesis.
Journal: Bioconjugate chemistry
Published: February 19, 2021
The Nonclinical Disposition and Pharmacokinetic/Pharmacodynamic Properties of N-Acetylgalactosamine-Conjugated Small Interfering RNA Are Highly Predictable and Build Confidence in Translation to Human.
Journal: Drug metabolism and disposition: the biological fate of chemicals
Published: February 16, 2021
RT-qPCR Methods to Support Pharmacokinetics and Drug Mechanism of Action to Advance Development of RNAi Therapeutics.
Journal: Nucleic acid therapeutics
Published: March 24, 2020
Last Updated: 09/26/2026