Kristina Althoff

Essen, NW, Germany

Last Updated: 09/26/2026

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Found 26 publications

Combined targeted and epigenetic-based therapy enhances antitumor immunity by stabilizing GATA6-dependent MHCI expression in pancreatic ductal adenocarcinoma.

Combined targeted and epigenetic-based therapy enhances antitumor immunity by stabilizing GATA6-dependent MHCI expression in pancreatic ductal adenocarcinoma.

Journal: Nature communications
Published: June 09, 2024

PLK1 blockade enhances the anti-tumor effect of MAPK inhibition in pancreatic ductal adenocarcinoma.

PLK1 blockade enhances the anti-tumor effect of MAPK inhibition in pancreatic ductal adenocarcinoma.

Journal: Cell reports
Published: January 19, 2024

Druggable epigenetic suppression of interferon-induced chemokine expression linked to MYCN amplification in neuroblastoma.

Druggable epigenetic suppression of interferon-induced chemokine expression linked to MYCN amplification in neuroblastoma.

Journal: Journal for immunotherapy of cancer
Published: April 13, 2021

Cellular model system to dissect the isoform-selectivity of Akt inhibitors.

Cellular model system to dissect the isoform-selectivity of Akt inhibitors.

Journal: Nature communications
Published: March 30, 2021

Progranulin mediates immune evasion of pancreatic ductal adenocarcinoma through regulation of MHCI expression.

Progranulin mediates immune evasion of pancreatic ductal adenocarcinoma through regulation of MHCI expression.

Journal: Nature communications
Published: March 07, 2021

Covalent-Allosteric Inhibitors to Achieve Akt Isoform-Selectivity.

Covalent-Allosteric Inhibitors to Achieve Akt Isoform-Selectivity.

Journal: Angewandte Chemie (International ed. in English)
Published: August 06, 2019

Synergistic activity of BET inhibitor MK-8628 and PLK inhibitor Volasertib in preclinical models of medulloblastoma.

Synergistic activity of BET inhibitor MK-8628 and PLK inhibitor Volasertib in preclinical models of medulloblastoma.

Journal: Cancer letters
Published: October 02, 2018

Notch-Induced Myeloid Reprogramming in Spontaneous Pancreatic Ductal Adenocarcinoma by Dual Genetic Targeting.

Notch-Induced Myeloid Reprogramming in Spontaneous Pancreatic Ductal Adenocarcinoma by Dual Genetic Targeting.

Journal: Cancer research
Published: January 07, 2018

ALK positively regulates MYCN activity through repression of HBP1 expression.

ALK positively regulates MYCN activity through repression of HBP1 expression.

Journal: Oncogene
Published: October 16, 2017

MYCN-mediated murine cancer models.

MYCN-mediated murine cancer models.

Journal: Aging
Published: March 31, 2017

Amplification of N-Myc is associated with a T-cell-poor microenvironment in metastatic neuroblastoma restraining interferon pathway activity and chemokine expression.

Amplification of N-Myc is associated with a T-cell-poor microenvironment in metastatic neuroblastoma restraining interferon pathway activity and chemokine expression.

Journal: Oncoimmunology
Published: December 13, 2016

Towards diagnostic application of non-coding RNAs in neuroblastoma.

Towards diagnostic application of non-coding RNAs in neuroblastoma.

Journal: Expert review of molecular diagnostics
Published: November 05, 2016
Showing 1-12 of 26

Last Updated: 09/26/2026