Kumarasamypet M. Mohankumar

Vellore, TN, India

Last Updated: 09/26/2026

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Found 17 publications

HLF and hTERT cooperatively enable partial immortalization of human hematopoietic stem and progenitor cells.

HLF and hTERT cooperatively enable partial immortalization of human hematopoietic stem and progenitor cells.

Journal: Frontiers in bioengineering and biotechnology

Published: October 24, 2025

Base-modified factor VIII mRNA delivery with galactosylated lipid nanoparticles as a protein replacement therapy for haemophilia A.

Base-modified factor VIII mRNA delivery with galactosylated lipid nanoparticles as a protein replacement therapy for haemophilia A.

Journal: Biomaterials science

Published: August 30, 2024

Enhanced fetal hemoglobin production via dual-beneficial mutation editing of the HBG promoter in hematopoietic stem and progenitor cells for β-hemoglobinopathies.

Enhanced fetal hemoglobin production via dual-beneficial mutation editing of the HBG promoter in hematopoietic stem and progenitor cells for β-hemoglobinopathies.

Journal: Stem cell research & therapy

Published: August 12, 2024

Editing of homologous globin genes by nickase-deficient base editor mitigates large intergenic deletions in HSPCs.

Editing of homologous globin genes by nickase-deficient base editor mitigates large intergenic deletions in HSPCs.

Journal: Molecular therapy. Nucleic acids

Published: December 02, 2023

SMART-lipid nanoparticles enabled mRNA vaccine elicits cross-reactive humoral responses against the omicron sub-variants.

SMART-lipid nanoparticles enabled mRNA vaccine elicits cross-reactive humoral responses against the omicron sub-variants.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy

Published: August 10, 2023

Protocol for arrayed gRNA screening by base editors in mammalian cell lines using lentiviral system.

Protocol for arrayed gRNA screening by base editors in mammalian cell lines using lentiviral system.

Journal: STAR protocols

Published: July 01, 2023

Base editing of key residues in the BCL11A-XL-specific zinc finger domains derepresses fetal globin expression.

Base editing of key residues in the BCL11A-XL-specific zinc finger domains derepresses fetal globin expression.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy

Published: April 28, 2023

Precise correction of a spectrum of β-thalassemia mutations in coding and non-coding regions by base editors.

Precise correction of a spectrum of β-thalassemia mutations in coding and non-coding regions by base editors.

Journal: Molecular therapy. Nucleic acids

Published: April 28, 2023

Editing the core region in HPFH deletions alters fetal and adult globin expression for treatment of β-hemoglobinopathies.

Editing the core region in HPFH deletions alters fetal and adult globin expression for treatment of β-hemoglobinopathies.

Journal: Molecular therapy. Nucleic acids

Published: December 17, 2022

Efficient and error-free correction of sickle mutation in human erythroid cells using prime editor-2.

Efficient and error-free correction of sickle mutation in human erythroid cells using prime editor-2.

Journal: Frontiers in genome editing

Published: October 31, 2022

Genome Engineering of Hematopoietic Stem Cells Using CRISPR/Cas9 System.

Genome Engineering of Hematopoietic Stem Cells Using CRISPR/Cas9 System.

Journal: Methods in molecular biology (Clifton, N.J.)

Published: May 04, 2022

Erythroid lineage-specific lentiviral RNAi vectors suitable for molecular functional studies and therapeutic applications.

Erythroid lineage-specific lentiviral RNAi vectors suitable for molecular functional studies and therapeutic applications.

Journal: Scientific reports

Published: March 05, 2022

Showing 1-12 of 17

Last Updated: 09/26/2026