Kuo-shyan Z. Lin

Vancouver, BC V5Z4E6, Canada

Last Updated: 09/26/2026

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Found 116 publications

Unnatural Amino Acid Substitutions to Improve In Vivo GRPR-Targeting Capability of [68Ga]Ga-SP01011 for Cancer Imaging.

Unnatural Amino Acid Substitutions to Improve In Vivo GRPR-Targeting Capability of [68Ga]Ga-SP01011 for Cancer Imaging.

Journal: Molecular pharmaceutics

Published: June 21, 2026

PSMA binding of carbamate-containing peptidomimetics influenced by side chain length and stereocenter configuration in preclinical prostate cancer model.

PSMA binding of carbamate-containing peptidomimetics influenced by side chain length and stereocenter configuration in preclinical prostate cancer model.

Journal: Bioorganic & medicinal chemistry

Published: May 08, 2026

Synthesis and evaluation of [68Ga]Ga-DOTA-Pip-PEP-4 derivatives for imaging gastrin-releasing peptide receptor expression with positron emission tomography.

Synthesis and evaluation of [68Ga]Ga-DOTA-Pip-PEP-4 derivatives for imaging gastrin-releasing peptide receptor expression with positron emission tomography.

Journal: Nuclear medicine and biology

Published: March 21, 2026

A simple solid-phase approach for the synthesis of DOTA-conjugated α-ketoamide-based fibroblast activation protein-targeted ligands.

A simple solid-phase approach for the synthesis of DOTA-conjugated α-ketoamide-based fibroblast activation protein-targeted ligands.

Journal: Bioorganic & medicinal chemistry letters

Published: March 08, 2026

Synthesis and Evaluation of Novel 68Ga-Labeled GRPR-Targeted PET Tracers Derived from [d-Phe6,Pro14]Bombesin(6-14) and [d-Phe6,des-Met14]Bombesin(6-14) Sequences.

Synthesis and Evaluation of Novel 68Ga-Labeled GRPR-Targeted PET Tracers Derived from [d-Phe6,Pro14]Bombesin(6-14) and [d-Phe6,des-Met14]Bombesin(6-14) Sequences.

Journal: Molecular pharmaceutics

Published: January 29, 2026

First-in-Human Evaluation of [68Ga]Ga-HTK03149, a PSMA-Targeted Tracer for PET Imaging in Prostate Cancer.

First-in-Human Evaluation of [68Ga]Ga-HTK03149, a PSMA-Targeted Tracer for PET Imaging in Prostate Cancer.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Published: October 26, 2025

Is Thiourea the Weak Link? An Investigation of the In Vitro and In Vivo Destabilization of [203Pb]- and [212Pb]Pb2+ Thiourea-Based Bioconjugates.

Is Thiourea the Weak Link? An Investigation of the In Vitro and In Vivo Destabilization of [203Pb]- and [212Pb]Pb2+ Thiourea-Based Bioconjugates.

Journal: ACS bio & med chem Au

Published: October 02, 2025

Synthesis and Preclinical Evaluation of Dual-Mode Fluorescent 18F-PET Tracers Targeting PSMA.

Synthesis and Preclinical Evaluation of Dual-Mode Fluorescent 18F-PET Tracers Targeting PSMA.

Journal: Journal of medicinal chemistry

Published: July 30, 2025

Development of an Optimized CXCR4-Targeting Theranostic Pair.

Development of an Optimized CXCR4-Targeting Theranostic Pair.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Published: April 25, 2025

Genetic risk in endolysosomal network genes correlates with endolysosomal dysfunction across neural cell types in Alzheimer's disease.

Genetic risk in endolysosomal network genes correlates with endolysosomal dysfunction across neural cell types in Alzheimer's disease.

Journal: bioRxiv : the preprint server for biology

Published: April 01, 2025

Novel 177Lu-Labeled [Thz14]Bombesin(6-14) Derivatives with Low Pancreas Accumulation for Targeting Gastrin-Releasing Peptide Receptor-Expressing Cancer.

Novel 177Lu-Labeled [Thz14]Bombesin(6-14) Derivatives with Low Pancreas Accumulation for Targeting Gastrin-Releasing Peptide Receptor-Expressing Cancer.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: March 05, 2025

Synthesis and Evaluation of 68Ga- and 177Lu-Labeled [diF-Pro14]Bombesin(6-14) Analogs for Detection and Radioligand Therapy of Gastrin-Releasing Peptide Receptor-Expressing Cancer.

Synthesis and Evaluation of 68Ga- and 177Lu-Labeled [diF-Pro14]Bombesin(6-14) Analogs for Detection and Radioligand Therapy of Gastrin-Releasing Peptide Receptor-Expressing Cancer.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: January 20, 2025

Showing 1-12 of 116

Last Updated: 09/26/2026