Kyoung M. Sim

Seoul, Republic of Korea

Last Updated: 09/26/2026

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Found 11 publications

CDK9 inhibitor A09-003 overcomes TRAIL resistance via dual Mcl-1 suppression in breast cancer cells.

CDK9 inhibitor A09-003 overcomes TRAIL resistance via dual Mcl-1 suppression in breast cancer cells.

Journal: Discover oncology

Published: September 25, 2025

High-throughput drug screening using a library of antibiotics targeting cancer cell lines that are resistant and sensitive to gemcitabine.

High-throughput drug screening using a library of antibiotics targeting cancer cell lines that are resistant and sensitive to gemcitabine.

Journal: Biochemical and biophysical research communications

Published: March 14, 2024

Understanding the molecular mechanism of pathogenic variants of BIR2 domain in XIAP-deficient inflammatory bowel disease.

Understanding the molecular mechanism of pathogenic variants of BIR2 domain in XIAP-deficient inflammatory bowel disease.

Journal: Scientific reports

Published: September 27, 2023

A new cyclin-dependent kinase-9 inhibitor A09-003 induces apoptosis in acute myeloid leukemia cells with reduction of myeloid cell leukemia sequence-1 protein.

A new cyclin-dependent kinase-9 inhibitor A09-003 induces apoptosis in acute myeloid leukemia cells with reduction of myeloid cell leukemia sequence-1 protein.

Journal: Chemico-biological interactions

Published: April 10, 2023

Decreased FAK activity and focal adhesion dynamics impair proper neurite formation of medium spiny neurons in Huntington's disease.

Decreased FAK activity and focal adhesion dynamics impair proper neurite formation of medium spiny neurons in Huntington's disease.

Journal: Acta neuropathologica

Published: March 25, 2022

Suppression of CaMKIIβ Inhibits ANO1-Mediated Glioblastoma Progression.

Suppression of CaMKIIβ Inhibits ANO1-Mediated Glioblastoma Progression.

Journal: Cells

Published: March 31, 2020

Aβ modulates actin cytoskeleton via SHIP2-mediated phosphoinositide metabolism.

Aβ modulates actin cytoskeleton via SHIP2-mediated phosphoinositide metabolism.

Journal: Scientific reports

Published: June 04, 2019

14-3-3γ Haploinsufficient Mice Display Hyperactive and Stress-sensitive Behaviors.

14-3-3γ Haploinsufficient Mice Display Hyperactive and Stress-sensitive Behaviors.

Journal: Experimental neurobiology

Published: December 09, 2018

In silico probing and biological evaluation of SETDB1/ESET-targeted novel compounds that reduce tri-methylated histone H3K9 (H3K9me3) level.

In silico probing and biological evaluation of SETDB1/ESET-targeted novel compounds that reduce tri-methylated histone H3K9 (H3K9me3) level.

Journal: Journal of computer-aided molecular design

Published: April 28, 2017

FRET-based Visualization of PDGF Receptor Activation at Membrane Microdomains.

FRET-based Visualization of PDGF Receptor Activation at Membrane Microdomains.

Journal: Scientific reports

Published: July 05, 2016

Synthesis of hybrid carbon nanotube structures coated with Sophora flavescens nanoparticles and their application to antimicrobial air filtration.

Synthesis of hybrid carbon nanotube structures coated with Sophora flavescens nanoparticles and their application to antimicrobial air filtration.

Journal: Journal of aerosol science

Published: August 11, 2014

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Last Updated: 09/26/2026