Lang Chen

Hubei Province Key Laboratory Of Allergy And Immunology And Department Of Immunology
Wuhan, 430071, China

Last Updated: 09/26/2026

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Found 22 publications

Pan-cancer 8q24 amplification predicts primary immunotherapy resistance and therapeutic vulnerabilities.

Pan-cancer 8q24 amplification predicts primary immunotherapy resistance and therapeutic vulnerabilities.

Journal: iScience
Published: December 20, 2025

Stratifin-mediated activation of AKT signaling and therapeutic targetability in hepatocellular carcinoma progression.

Stratifin-mediated activation of AKT signaling and therapeutic targetability in hepatocellular carcinoma progression.

Journal: Cell insight
Published: April 10, 2024

Upregulation of miR-520c-3p via hepatitis B virus drives hepatocellular migration and invasion by the PTEN/AKT/NF-κB axis.

Upregulation of miR-520c-3p via hepatitis B virus drives hepatocellular migration and invasion by the PTEN/AKT/NF-κB axis.

Journal: Molecular therapy. Nucleic acids
Published: October 30, 2021

HBV X Protein Induces Degradation of UBXN7, a Novel Negative Regulator of NF-κB Signaling, to Promote HBV Replication.

HBV X Protein Induces Degradation of UBXN7, a Novel Negative Regulator of NF-κB Signaling, to Promote HBV Replication.

Journal: Cellular and molecular gastroenterology and hepatology
Published: August 03, 2021

PTEN suppresses tumorigenesis by directly dephosphorylating Akt.

PTEN suppresses tumorigenesis by directly dephosphorylating Akt.

Journal: Signal transduction and targeted therapy
Published: November 03, 2020

The Ubiquitin E3 Ligase Parkin Inhibits Innate Antiviral Immunity Through K48-Linked Polyubiquitination of RIG-I and MDA5.

The Ubiquitin E3 Ligase Parkin Inhibits Innate Antiviral Immunity Through K48-Linked Polyubiquitination of RIG-I and MDA5.

Journal: Frontiers in immunology
Published: April 08, 2020

MxB impedes the NUP358-mediated HIV-1 pre-integration complex nuclear import and viral replication cooperatively with CPSF6.

MxB impedes the NUP358-mediated HIV-1 pre-integration complex nuclear import and viral replication cooperatively with CPSF6.

Journal: Retrovirology
Published: March 17, 2020

Suppression of HIV-1 Integration by Targeting HIV-1 Integrase for Degradation with A Chimeric Ubiquitin Ligase.

Suppression of HIV-1 Integration by Targeting HIV-1 Integrase for Degradation with A Chimeric Ubiquitin Ligase.

Journal: Virologica Sinica
Published: March 14, 2020

Elevated expression of miR-146a correlates with high levels of immune cell exhaustion markers and suppresses cellular immune function in chronic HIV-1-infected patients.

Elevated expression of miR-146a correlates with high levels of immune cell exhaustion markers and suppresses cellular immune function in chronic HIV-1-infected patients.

Journal: Scientific reports
Published: August 08, 2019

Hepatitis B virus-regulated growth of liver cancer cells occurs through the microRNA-340-5p-activating transcription factor 7-heat shock protein A member 1B axis.

Hepatitis B virus-regulated growth of liver cancer cells occurs through the microRNA-340-5p-activating transcription factor 7-heat shock protein A member 1B axis.

Journal: Cancer science
Published: January 04, 2019

HIV-1-Induced miR-146a Attenuates Monocyte Migration by Targeting CCL5 in Human Primary Macrophages.

HIV-1-Induced miR-146a Attenuates Monocyte Migration by Targeting CCL5 in Human Primary Macrophages.

Journal: AIDS research and human retroviruses
Published: May 03, 2018

Short Communication: Long Noncoding RNA GAS5 Inhibits HIV-1 Replication Through Interaction with miR-873.

Short Communication: Long Noncoding RNA GAS5 Inhibits HIV-1 Replication Through Interaction with miR-873.

Journal: AIDS research and human retroviruses
Published: April 06, 2018
Showing 1-12 of 22

Last Updated: 09/26/2026