Lars H. Edvinsson

Lund, M, Sweden

Last Updated: 09/26/2026

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Found 248 publications

Substance P and PACAP activate dural mast cells through MRGPRX2, not NK1R or PAC1/VPAC receptors.

Substance P and PACAP activate dural mast cells through MRGPRX2, not NK1R or PAC1/VPAC receptors.

Journal: Cephalalgia : an international journal of headache

Published: August 21, 2026

Nociceptive action of calcitonin gene-related peptide in the trigeminovascular system.

Nociceptive action of calcitonin gene-related peptide in the trigeminovascular system.

Journal: Nature reviews. Neurology

Published: April 27, 2026

CGRP-targeted migraine treatment and early pathophysiology in experimental subarachnoid hemorrhage.

CGRP-targeted migraine treatment and early pathophysiology in experimental subarachnoid hemorrhage.

Journal: The journal of headache and pain

Published: April 06, 2026

Understanding RAMP1's role in hormonal migraine may improve CGRP-targeted therapies.

Understanding RAMP1's role in hormonal migraine may improve CGRP-targeted therapies.

Journal: Expert review of clinical pharmacology

Published: January 28, 2026

Hypothalamic and sex-related hormones in migraine.

Hypothalamic and sex-related hormones in migraine.

Journal: The journal of headache and pain

Published: December 09, 2025

Expression of melatonin receptors in trigeminal and sphenopalatine ganglia: potential targets for primary headache disorders.

Expression of melatonin receptors in trigeminal and sphenopalatine ganglia: potential targets for primary headache disorders.

Journal: The journal of headache and pain

Published: September 05, 2025

Is PACAP the next big thing in migraine therapy?

Is PACAP the next big thing in migraine therapy?

Journal: Cephalalgia : an international journal of headache

Published: August 18, 2025

RAMP1-dependent hormonal regulation of CGRP and its receptor in the trigeminal ganglion.

RAMP1-dependent hormonal regulation of CGRP and its receptor in the trigeminal ganglion.

Journal: The journal of headache and pain

Published: April 15, 2025

Independent and synergistic roles of MEK-ERK1/2 and PKC pathways in regulating functional changes in vascular tissue following flow cessation.

Independent and synergistic roles of MEK-ERK1/2 and PKC pathways in regulating functional changes in vascular tissue following flow cessation.

Journal: Journal of molecular and cellular cardiology plus

Published: April 08, 2025

Ex vivo stimulation of the trigeminal nucleus caudalis induces peripheral CGRP release in the trigeminal ganglion and reveals a distinct dopamine-endocannabinoid mechanism relevant to migraine.

Ex vivo stimulation of the trigeminal nucleus caudalis induces peripheral CGRP release in the trigeminal ganglion and reveals a distinct dopamine-endocannabinoid mechanism relevant to migraine.

Journal: The journal of headache and pain

Published: March 28, 2025

TRPM3 activation causes CGRP release in trigeminal neurons: Implications for migraine mechanisms.

TRPM3 activation causes CGRP release in trigeminal neurons: Implications for migraine mechanisms.

Journal: Headache

Published: January 28, 2025

Revisiting substance P in migraine: a methodological approach inspired by anti-CGRP and anti-PACAP success.

Revisiting substance P in migraine: a methodological approach inspired by anti-CGRP and anti-PACAP success.

Journal: The journal of headache and pain

Published: December 31, 2024

Showing 1-12 of 248

Last Updated: 09/26/2026