Lars L. Lannfelt

Lars L. Lannfelt

Uppsala Science Park
Uppsala, C 75185, Sweden

Last Updated: 09/26/2026

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Found 132 publications

Lecanemab promotes Fc receptor-dependent cell-mediated internalization and degradation of aggregated amyloid-beta in vitro and ex vivo.

Lecanemab promotes Fc receptor-dependent cell-mediated internalization and degradation of aggregated amyloid-beta in vitro and ex vivo.

Journal: Neuroscience letters

Published: February 18, 2026

MALDI mass spectrometry imaging (MSI) reveals molecular and structural heterogeneity of amyloid-β in sporadic Alzheimer's disease and Down syndrome.

MALDI mass spectrometry imaging (MSI) reveals molecular and structural heterogeneity of amyloid-β in sporadic Alzheimer's disease and Down syndrome.

Journal: Acta neuropathologica communications

Published: December 08, 2025

The Uppsala APP Mutation Promotes Wild-Type Amyloid-β Aggregation and Deposition In Vivo.

The Uppsala APP Mutation Promotes Wild-Type Amyloid-β Aggregation and Deposition In Vivo.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: July 28, 2025

Exidavnemab binds to aggregated α-synuclein in human brains affected by α-synucleinopathies.

Exidavnemab binds to aggregated α-synuclein in human brains affected by α-synucleinopathies.

Journal: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics

Published: June 30, 2025

Endogenously generated Dutch-type Aβ non-fibrillar aggregates dysregulate presynaptic neurotransmission in the absence of detectable inflammation.

Endogenously generated Dutch-type Aβ non-fibrillar aggregates dysregulate presynaptic neurotransmission in the absence of detectable inflammation.

Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association

Published: March 13, 2025

Endogenously generated Dutch-type Aβ nonfibrillar aggregates dysregulate presynaptic neurotransmission in the absence of detectable inflammation.

Endogenously generated Dutch-type Aβ nonfibrillar aggregates dysregulate presynaptic neurotransmission in the absence of detectable inflammation.

Journal: bioRxiv : the preprint server for biology

Published: March 10, 2025

Point of view: Challenges in implementation of new immunotherapies for Alzheimer's disease.

Point of view: Challenges in implementation of new immunotherapies for Alzheimer's disease.

Journal: The journal of prevention of Alzheimer's disease

Published: October 28, 2024

Disease modifying effects of the amyloid-beta protofibril-selective antibody mAb158 in aged Tg2576 transgenic mice.

Disease modifying effects of the amyloid-beta protofibril-selective antibody mAb158 in aged Tg2576 transgenic mice.

Journal: Molecular and cellular neurosciences

Published: April 04, 2024

Lecanemab demonstrates highly selective binding to Aβ protofibrils isolated from Alzheimer's disease brains.

Lecanemab demonstrates highly selective binding to Aβ protofibrils isolated from Alzheimer's disease brains.

Journal: Molecular and cellular neurosciences

Published: March 28, 2024

Amyloid-beta antibody binding to cerebral amyloid angiopathy fibrils and risk for amyloid-related imaging abnormalities.

Amyloid-beta antibody binding to cerebral amyloid angiopathy fibrils and risk for amyloid-related imaging abnormalities.

Journal: Scientific reports

Published: December 22, 2023

A light at the end of the tunnel - from mutation identification to a potential treatment for Alzheimer's disease.

A light at the end of the tunnel - from mutation identification to a potential treatment for Alzheimer's disease.

Journal: Upsala journal of medical sciences

Published: October 20, 2023

Altered amyloid-β structure markedly reduces gliosis in the brain of mice harboring the Uppsala APP deletion.

Altered amyloid-β structure markedly reduces gliosis in the brain of mice harboring the Uppsala APP deletion.

Journal: Acta neuropathologica communications

Published: October 17, 2023

Showing 1-12 of 132

Last Updated: 09/26/2026