Laste Stojanovski

Dundee, SCT DD15EH, United Kingdom

Last Updated: 09/26/2026

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Found 37 publications

Use of a cytochrome P450 humanized mouse model to refine schistosomiasis drug discovery.

Use of a cytochrome P450 humanized mouse model to refine schistosomiasis drug discovery.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: April 10, 2026

Application of a mouse model humanized for cytochrome P450-mediated drug metabolism to predict drug-drug interactions between a peptide and small molecule drugs.

Application of a mouse model humanized for cytochrome P450-mediated drug metabolism to predict drug-drug interactions between a peptide and small molecule drugs.

Journal: Drug metabolism and disposition: the biological fate of chemicals

Published: June 06, 2025

Structure-Guided Design and Synthesis of a Pyridazinone Series of Trypanosoma cruzi Proteasome Inhibitors.

Structure-Guided Design and Synthesis of a Pyridazinone Series of Trypanosoma cruzi Proteasome Inhibitors.

Journal: Journal of medicinal chemistry

Published: July 28, 2023

Author Correction: Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis.

Author Correction: Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis.

Journal: Nature

Published: July 04, 2023

Development of a 2,4-Diaminothiazole Series for the Treatment of Human African Trypanosomiasis Highlights the Importance of Static-Cidal Screening of Analogues.

Development of a 2,4-Diaminothiazole Series for the Treatment of Human African Trypanosomiasis Highlights the Importance of Static-Cidal Screening of Analogues.

Journal: Journal of medicinal chemistry

Published: June 21, 2023

Lysyl-tRNA synthetase, a target for urgently needed M. tuberculosis drugs.

Lysyl-tRNA synthetase, a target for urgently needed M. tuberculosis drugs.

Journal: Nature communications

Published: April 12, 2022

Repositioning of a Diaminothiazole Series Confirmed to Target the Cyclin-Dependent Kinase CRK12 for Use in the Treatment of African Animal Trypanosomiasis.

Repositioning of a Diaminothiazole Series Confirmed to Target the Cyclin-Dependent Kinase CRK12 for Use in the Treatment of African Animal Trypanosomiasis.

Journal: Journal of medicinal chemistry

Published: March 18, 2022

Identification and development of a series of disubstituted piperazines for the treatment of Chagas disease.

Identification and development of a series of disubstituted piperazines for the treatment of Chagas disease.

Journal: European journal of medicinal chemistry

Published: February 15, 2022

Optimization of TAM16, a Benzofuran That Inhibits the Thioesterase Activity of Pks13; Evaluation toward a Preclinical Candidate for a Novel Antituberculosis Clinical Target.

Optimization of TAM16, a Benzofuran That Inhibits the Thioesterase Activity of Pks13; Evaluation toward a Preclinical Candidate for a Novel Antituberculosis Clinical Target.

Journal: Journal of medicinal chemistry

Published: December 15, 2021

Scaffold-Hopping Strategy on a Series of Proteasome Inhibitors Led to a Preclinical Candidate for the Treatment of Visceral Leishmaniasis.

Scaffold-Hopping Strategy on a Series of Proteasome Inhibitors Led to a Preclinical Candidate for the Treatment of Visceral Leishmaniasis.

Journal: Journal of medicinal chemistry

Published: April 27, 2021

Identification and Optimization of a Series of 8-Hydroxy Naphthyridines with Potent In Vitro Antileishmanial Activity: Initial SAR and Assessment of In Vivo Activity.

Identification and Optimization of a Series of 8-Hydroxy Naphthyridines with Potent In Vitro Antileishmanial Activity: Initial SAR and Assessment of In Vivo Activity.

Journal: Journal of medicinal chemistry

Published: July 15, 2020

Identification of 6-amino-1H-pyrazolo[3,4-d]pyrimidines with in vivo efficacy against visceral leishmaniasis.

Identification of 6-amino-1H-pyrazolo[3,4-d]pyrimidines with in vivo efficacy against visceral leishmaniasis.

Journal: RSC medicinal chemistry

Published: June 12, 2020

Showing 1-12 of 37

Last Updated: 09/26/2026