Laszlo Orfi

Budapest, BU, Hungary

Last Updated: 09/26/2026

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Found 58 publications

Identification and Validation of an Inhibitor of the Protein Kinases PIM and DYRK.

Identification and Validation of an Inhibitor of the Protein Kinases PIM and DYRK.

Journal: Journal of medicinal chemistry
Published: March 18, 2026

Identification and Validation of an inhibitor of the protein kinases PIM and DYRK.

Identification and Validation of an inhibitor of the protein kinases PIM and DYRK.

Journal: bioRxiv : the preprint server for biology
Published: November 24, 2025

Novel Sigma-1 receptor agonist alleviates renal ischemic injury by targeting apoptotic and inflammatory pathways.

Novel Sigma-1 receptor agonist alleviates renal ischemic injury by targeting apoptotic and inflammatory pathways.

Journal: Scientific reports
Published: June 06, 2025

Improvement in Transient Agarose Spot (TAS) Cell Migration Assay: Microplate-Based Detection and Evaluation.

Improvement in Transient Agarose Spot (TAS) Cell Migration Assay: Microplate-Based Detection and Evaluation.

Journal: International journal of molecular sciences
Published: April 30, 2025

The role of PI3K-Akt-mTOR axis in Warburg effect and its modification by specific protein kinase inhibitors in human and rat inflammatory macrophages.

The role of PI3K-Akt-mTOR axis in Warburg effect and its modification by specific protein kinase inhibitors in human and rat inflammatory macrophages.

Journal: International immunopharmacology
Published: February 29, 2024

CDK9 inhibition as an effective therapy for small cell lung cancer.

CDK9 inhibition as an effective therapy for small cell lung cancer.

Journal: Cell death & disease
Published: November 13, 2023

Optimization of Sirius Red-Based Microplate Assay to Investigate Collagen Production In Vitro.

Optimization of Sirius Red-Based Microplate Assay to Investigate Collagen Production In Vitro.

Journal: International journal of molecular sciences
Published: November 04, 2023

Sigma-1 Receptor Agonist Fluvoxamine Ameliorates Fibrotic Response of Trabecular Meshwork Cells.

Sigma-1 Receptor Agonist Fluvoxamine Ameliorates Fibrotic Response of Trabecular Meshwork Cells.

Journal: International journal of molecular sciences
Published: June 01, 2023

Synthesis and evaluation of a new class of MIF-inhibitors in activated macrophage cells and in experimental septic shock in mice.

Synthesis and evaluation of a new class of MIF-inhibitors in activated macrophage cells and in experimental septic shock in mice.

Journal: European journal of medicinal chemistry
Published: October 19, 2022

Decreasing effects of protein kinase inhibitors on the expression of NOS2 and inflammatory cytokines and on phagocytosis in rat peritoneal macrophages is partly related to repolarization.

Decreasing effects of protein kinase inhibitors on the expression of NOS2 and inflammatory cytokines and on phagocytosis in rat peritoneal macrophages is partly related to repolarization.

Journal: Molecular immunology
Published: August 22, 2022

Transient Agarose Spot (TAS) Assay: A New Method to Investigate Cell Migration.

Transient Agarose Spot (TAS) Assay: A New Method to Investigate Cell Migration.

Journal: International journal of molecular sciences
Published: December 21, 2021

Production of NOS2 and inflammatory cytokines is reduced by selected protein kinase inhibitors with partial repolarization of HL-60 derived and human blood macrophages.

Production of NOS2 and inflammatory cytokines is reduced by selected protein kinase inhibitors with partial repolarization of HL-60 derived and human blood macrophages.

Journal: Heliyon
Published: July 12, 2021
Showing 1-12 of 58

Last Updated: 09/26/2026