Laura E. Jenkins

Glasgow, SCT G128QQ, United Kingdom

Last Updated: 09/26/2026

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Found 37 publications

Allosteric ligands with distinct properties uncover tissue-specific physiological regulation mediated by free fatty acid receptor 2.

Allosteric ligands with distinct properties uncover tissue-specific physiological regulation mediated by free fatty acid receptor 2.

Journal: Science signaling

Published: June 30, 2026

Mechanism of GPR84 allosteric modulation at a helix 8-proximate site.

Mechanism of GPR84 allosteric modulation at a helix 8-proximate site.

Journal: bioRxiv : the preprint server for biology

Published: April 17, 2026

Discovery, Structure-Activity Relationship, and Functional Characterization of a Chromenopyrrole Series as Orthosteric Antagonists of GPR84.

Discovery, Structure-Activity Relationship, and Functional Characterization of a Chromenopyrrole Series as Orthosteric Antagonists of GPR84.

Journal: Journal of medicinal chemistry

Published: March 23, 2026

Steric control of signaling bias in the immunometabolic receptor GPR84.

Steric control of signaling bias in the immunometabolic receptor GPR84.

Journal: bioRxiv : the preprint server for biology

Published: August 06, 2025

Dehydroxylate I formation from the thermal decomposition of serpentine on c-complex asteroids: similarities to carlosturanite.

Dehydroxylate I formation from the thermal decomposition of serpentine on c-complex asteroids: similarities to carlosturanite.

Journal: Earth, planets, and space : EPS

Published: April 15, 2025

Allosteric modulation and biased signalling at free fatty acid receptor 2.

Allosteric modulation and biased signalling at free fatty acid receptor 2.

Journal: Nature

Published: August 08, 2024

A high-resolution in situ X-ray diffraction study of mineral transitions due to post-hydration heating in CM chondrite meteorites.

A high-resolution in situ X-ray diffraction study of mineral transitions due to post-hydration heating in CM chondrite meteorites.

Journal: Earth, planets, and space : EPS

Published: July 15, 2024

Structure-Activity Relationship Studies and Optimization of 4-Hydroxypyridones as GPR84 Agonists.

Structure-Activity Relationship Studies and Optimization of 4-Hydroxypyridones as GPR84 Agonists.

Journal: Journal of medicinal chemistry

Published: February 21, 2024

Structural basis for the ligand recognition and signaling of free fatty acid receptors.

Structural basis for the ligand recognition and signaling of free fatty acid receptors.

Journal: Science advances

Published: January 10, 2024

Phosphorylation bar-coding of free fatty acid receptor 2 is generated in a tissue-specific manner.

Phosphorylation bar-coding of free fatty acid receptor 2 is generated in a tissue-specific manner.

Journal: eLife

Published: December 12, 2023

Structural basis for the ligand recognition and signaling of free fatty acid receptors.

Structural basis for the ligand recognition and signaling of free fatty acid receptors.

Journal: bioRxiv : the preprint server for biology

Published: September 04, 2023

Discovery of Potent Tetrazole Free Fatty Acid Receptor 2 Antagonists.

Discovery of Potent Tetrazole Free Fatty Acid Receptor 2 Antagonists.

Journal: Journal of medicinal chemistry

Published: May 02, 2023

Showing 1-12 of 37

Last Updated: 09/26/2026