Laura Frame
Dundee, SCT DD15EH, United Kingdom
Last Updated: 09/26/2026
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Found 11 publications
Use of a cytochrome P450 humanized mouse model to refine schistosomiasis drug discovery.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: April 10, 2026
Humanization of Drug Metabolism in the Plasmodium berghei Mouse Model for Antimalarial Drug Discovery.
Journal: ACS infectious diseases
Published: December 01, 2025
Hedera helix-derived α-hederin (IVL-11) demonstrates both ex vivo and in vivo flukicidal activities against Fasciola hepatica.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Published: November 04, 2025
Antitrypanosomal quinazolines targeting lysyl-tRNA synthetase show partial efficacy in a mouse model of acute Chagas disease.
Journal: Science translational medicine
Published: July 09, 2025
Application of a mouse model humanized for cytochrome P450-mediated drug metabolism to predict drug-drug interactions between a peptide and small molecule drugs.
Journal: Drug metabolism and disposition: the biological fate of chemicals
Published: June 06, 2025
Structure-activity relationships of 1,5-dihydro-2H-benzo[b][1,4]diazepine-2,4(3H)-diones as inhibitors of Trypanosoma cruzi.
Journal: RSC medicinal chemistry
Published: February 28, 2025
Use of an extensively humanized mouse model to predict the risk of drug-drug interactions in patients receiving dexamethasone.
Journal: The Journal of pharmacology and experimental therapeutics
Published: November 24, 2024
Cryptosporidium lysyl-tRNA synthetase inhibitors define the interplay between solubility and permeability required to achieve efficacy.
Journal: Science translational medicine
Published: October 23, 2024
Acceleration of infectious disease drug discovery and development using a humanized model of drug metabolism.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: February 05, 2024
Structure-Guided Design and Synthesis of a Pyridazinone Series of Trypanosoma cruzi Proteasome Inhibitors.
Journal: Journal of medicinal chemistry
Published: July 28, 2023
Development of a label-free Raman imaging technique for differentiation of malaria parasite infected from non-infected tissue.
Journal: The Analyst
Published: November 17, 2017
Showing 1-11 of 11
Last Updated: 09/26/2026