Laura H. Heitman

Leiden, ZH 2333CC, Netherlands

Last Updated: 09/26/2026

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Found 160 publications

Enterochromaffin cells as a cellular integration hub for cooperative microbial signaling to modulate gut serotonin and motility.

Enterochromaffin cells as a cellular integration hub for cooperative microbial signaling to modulate gut serotonin and motility.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: August 24, 2026

From dual norepinephrine-dopamine reuptake inhibition to selective dopamine reuptake inhibitors: a case of aromatically substituted N,2-cyclopentylamines.

From dual norepinephrine-dopamine reuptake inhibition to selective dopamine reuptake inhibitors: a case of aromatically substituted N,2-cyclopentylamines.

Journal: RSC medicinal chemistry

Published: February 10, 2026

The Concise Guide to PHARMACOLOGY 2025/26: G protein-coupled receptors.

The Concise Guide to PHARMACOLOGY 2025/26: G protein-coupled receptors.

Journal: British journal of pharmacology

Published: December 29, 2025

Exploring the binding kinetics of intracellular allosteric antagonists for CC chemokine receptor 2 - a key to improve insurmountable antagonism.

Exploring the binding kinetics of intracellular allosteric antagonists for CC chemokine receptor 2 - a key to improve insurmountable antagonism.

Journal: Biochemical pharmacology

Published: December 19, 2025

Impedance-based phenotypic profiling of metabotropic glutamate receptor ligand responses in SCA1 human iPSC-derived neuronal cultures.

Impedance-based phenotypic profiling of metabotropic glutamate receptor ligand responses in SCA1 human iPSC-derived neuronal cultures.

Journal: Neurobiology of disease

Published: December 17, 2025

Leveraging Targeted Protein Degradation for G Protein-Coupled Receptors: The Development of CCR2 Molecular Degraders.

Leveraging Targeted Protein Degradation for G Protein-Coupled Receptors: The Development of CCR2 Molecular Degraders.

Journal: Journal of medicinal chemistry

Published: December 11, 2025

Combining AlphaFold with Focused Virtual Library Design in the Development of Novel CCR2 and CCR5 Antagonists.

Combining AlphaFold with Focused Virtual Library Design in the Development of Novel CCR2 and CCR5 Antagonists.

Journal: Journal of chemical information and modeling

Published: November 12, 2025

Kinetic multiplex assay to assess biased signaling of clinical GPCR agonists.

Kinetic multiplex assay to assess biased signaling of clinical GPCR agonists.

Journal: Pharmacological research

Published: September 08, 2025

Reply.

Reply.

Journal: Arthritis & rheumatology (Hoboken, N.J.)

Published: July 14, 2025

Toward Assay-Aware Bioactivity Model(er)s: Getting a Grip on Biological Context.

Toward Assay-Aware Bioactivity Model(er)s: Getting a Grip on Biological Context.

Journal: Journal of chemical information and modeling

Published: June 30, 2025

The endocannabinoid 2-arachidonoylglycerol is released and transported on demand via extracellular microvesicles.

The endocannabinoid 2-arachidonoylglycerol is released and transported on demand via extracellular microvesicles.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: February 20, 2025

GPCR-G protein signalling and its mutational landscape in cancer-Driver or passenger.

GPCR-G protein signalling and its mutational landscape in cancer-Driver or passenger.

Journal: British journal of pharmacology

Published: February 04, 2025

Showing 1-12 of 160

Last Updated: 09/26/2026