Laura N. Jeffreys

Manchester, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 16 publications

Second-Generation Anti-Tubercular Squaramides Targeting Complex V of the Respiratory Chain of Mycobacterium tuberculosis Displaying Enhanced Metabolic Stability.

Second-Generation Anti-Tubercular Squaramides Targeting Complex V of the Respiratory Chain of Mycobacterium tuberculosis Displaying Enhanced Metabolic Stability.

Journal: Journal of medicinal chemistry

Published: April 23, 2026

Integrated structural dynamics uncover a new B12 photoreceptor activation mode.

Integrated structural dynamics uncover a new B12 photoreceptor activation mode.

Journal: Nature

Published: August 01, 2025

SignatureFinder enables sequence mining to identify cobalamin-dependent photoreceptor proteins.

SignatureFinder enables sequence mining to identify cobalamin-dependent photoreceptor proteins.

Journal: The FEBS journal

Published: July 05, 2024

Lack of antiviral activity of probenecid in vitro and in Syrian golden hamsters.

Lack of antiviral activity of probenecid in vitro and in Syrian golden hamsters.

Journal: The Journal of antimicrobial chemotherapy

Published: October 10, 2023

Photocobilins integrate B12 and bilin photochemistry for enzyme control.

Photocobilins integrate B12 and bilin photochemistry for enzyme control.

Journal: Nature communications

Published: May 18, 2023

Redox driven B12-ligand switch drives CarH photoresponse.

Redox driven B12-ligand switch drives CarH photoresponse.

Journal: Nature communications

Published: February 15, 2023

Lack of antiviral activity of probenecid in Vero E6 cells and Syrian golden hamsters: a need for better understanding of inter-lab differences in preclinical assays.

Lack of antiviral activity of probenecid in Vero E6 cells and Syrian golden hamsters: a need for better understanding of inter-lab differences in preclinical assays.

Journal: bioRxiv : the preprint server for biology

Published: March 09, 2022

Interaction of the new inhibitor paxlovid (PF-07321332) and ivermectin with the monomer of the main protease SARS-CoV-2: A volumetric study based on molecular dynamics, elastic networks, classical thermodynamics and SPT.

Interaction of the new inhibitor paxlovid (PF-07321332) and ivermectin with the monomer of the main protease SARS-CoV-2: A volumetric study based on molecular dynamics, elastic networks, classical thermodynamics and SPT.

Journal: Computational biology and chemistry

Published: January 04, 2022

Comparative study of SARS-CoV-2 infection in different cell types: Biophysical-computational approach to the role of potential receptors.

Comparative study of SARS-CoV-2 infection in different cell types: Biophysical-computational approach to the role of potential receptors.

Journal: Computers in biology and medicine

Published: December 14, 2021

A Promiscuous Bacterial P450: The Unparalleled Diversity of BM3 in Pharmaceutical Metabolism.

A Promiscuous Bacterial P450: The Unparalleled Diversity of BM3 in Pharmaceutical Metabolism.

Journal: International journal of molecular sciences

Published: September 13, 2021

Remdesivir-ivermectin combination displays synergistic interaction with improved in vitro activity against SARS-CoV-2.

Remdesivir-ivermectin combination displays synergistic interaction with improved in vitro activity against SARS-CoV-2.

Journal: International journal of antimicrobial agents

Published: September 09, 2021

Comparative study of the interaction of ivermectin with proteins of interest associated with SARS-CoV-2: A computational and biophysical approach.

Comparative study of the interaction of ivermectin with proteins of interest associated with SARS-CoV-2: A computational and biophysical approach.

Journal: Biophysical chemistry

Published: April 29, 2021

Showing 1-12 of 16

Last Updated: 09/26/2026