Laura Raccosta

Via Olgettina, 58-20132
Milan, 20132, Italy

Last Updated: 09/26/2026

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Found 11 publications

Discovery of 22(S)-23-phenyl-24-norchol-5-en-3β,22-diol (PFM046) as the first-in-class, steroidal, non-sulfated Liver X Receptor antagonist with anticancer activity.

Discovery of 22(S)-23-phenyl-24-norchol-5-en-3β,22-diol (PFM046) as the first-in-class, steroidal, non-sulfated Liver X Receptor antagonist with anticancer activity.

Journal: European journal of medicinal chemistry

Published: July 26, 2024

LIM-domain-only 4 (LMO4) enhances CD8+ T-cell stemness and tumor rejection by boosting IL-21-STAT3 signaling.

LIM-domain-only 4 (LMO4) enhances CD8+ T-cell stemness and tumor rejection by boosting IL-21-STAT3 signaling.

Journal: Signal transduction and targeted therapy

Published: December 01, 2023

Harnessing the reverse cholesterol transport pathway to favor differentiation of monocyte-derived APCs and antitumor responses.

Harnessing the reverse cholesterol transport pathway to favor differentiation of monocyte-derived APCs and antitumor responses.

Journal: Cell death & disease

Published: December 01, 2022

Therapeutic Regeneration of Lymphatic and Immune Cell Functions upon Lympho-organoid Transplantation.

Therapeutic Regeneration of Lymphatic and Immune Cell Functions upon Lympho-organoid Transplantation.

Journal: Stem cell reports

Published: March 07, 2019

Nuclear receptor ligands induce TREM-1 expression on dendritic cells: analysis of their role in tumors.

Nuclear receptor ligands induce TREM-1 expression on dendritic cells: analysis of their role in tumors.

Journal: Oncoimmunology

Published: May 25, 2018

Enzymatic Inactivation of Oxysterols in Breast Tumor Cells Constraints Metastasis Formation by Reprogramming the Metastatic Lung Microenvironment.

Enzymatic Inactivation of Oxysterols in Breast Tumor Cells Constraints Metastasis Formation by Reprogramming the Metastatic Lung Microenvironment.

Journal: Frontiers in immunology

Published: February 01, 2018

24-Hydroxycholesterol participates in pancreatic neuroendocrine tumor development.

24-Hydroxycholesterol participates in pancreatic neuroendocrine tumor development.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: September 28, 2016

The administration of drugs inhibiting cholesterol/oxysterol synthesis is safe and increases the efficacy of immunotherapeutic regimens in tumor-bearing mice.

The administration of drugs inhibiting cholesterol/oxysterol synthesis is safe and increases the efficacy of immunotherapeutic regimens in tumor-bearing mice.

Journal: Cancer immunology, immunotherapy : CII

Published: March 04, 2016

Cholesterol metabolites and tumor microenvironment: the road towards clinical translation.

Cholesterol metabolites and tumor microenvironment: the road towards clinical translation.

Journal: Cancer immunology, immunotherapy : CII

Published: July 21, 2015

Oxysterols recruit tumor-supporting neutrophils within the tumor microenvironment: The many facets of tumor-derived oxysterols.

Oxysterols recruit tumor-supporting neutrophils within the tumor microenvironment: The many facets of tumor-derived oxysterols.

Journal: Oncoimmunology

Published: September 10, 2013

The oxysterol-CXCR2 axis plays a key role in the recruitment of tumor-promoting neutrophils.

The oxysterol-CXCR2 axis plays a key role in the recruitment of tumor-promoting neutrophils.

Journal: The Journal of experimental medicine

Published: July 31, 2013

Showing 1-11 of 11

Last Updated: 09/26/2026