Laura Scalvini

Parma, Italy

Last Updated: 09/26/2026

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Found 44 publications

Iso- and Benzisothiazolinone Inhibitors of Monoacylglycerol Lipase: Exploring On-Target Activity Through Scaffold Decoration and In Situ Warhead Generation.

Iso- and Benzisothiazolinone Inhibitors of Monoacylglycerol Lipase: Exploring On-Target Activity Through Scaffold Decoration and In Situ Warhead Generation.

Journal: ChemMedChem

Published: May 26, 2026

The rare bile acid isoallolithocholic acid (IALCA) is an EphA2 antagonist sparing FXR and TGR5 receptors.

The rare bile acid isoallolithocholic acid (IALCA) is an EphA2 antagonist sparing FXR and TGR5 receptors.

Journal: Biochemical pharmacology

Published: December 18, 2025

N-Acylaminoethyltetrahydroquinolines: A new class of melatonin receptor ligands with in vivo activity on glioblastoma.

N-Acylaminoethyltetrahydroquinolines: A new class of melatonin receptor ligands with in vivo activity on glioblastoma.

Journal: European journal of medicinal chemistry

Published: August 11, 2025

New Vanillyl-capped HDAC inhibitors exhibit anti-tumor efficacy in neuroblastoma and glioblastoma cells.

New Vanillyl-capped HDAC inhibitors exhibit anti-tumor efficacy in neuroblastoma and glioblastoma cells.

Journal: Bioorganic chemistry

Published: July 30, 2025

Dual targeting of EphAs and KDR axis hampers VEGF-induced angiogenesis and glioma stem cell replication.

Dual targeting of EphAs and KDR axis hampers VEGF-induced angiogenesis and glioma stem cell replication.

Journal: Biochemical pharmacology

Published: May 29, 2025

Identification of pyrazolo-piperidinone derivatives targeting YAP-TEAD interface 3 as anticancer agents through integrated virtual screening and mass spectrometry proteomics.

Identification of pyrazolo-piperidinone derivatives targeting YAP-TEAD interface 3 as anticancer agents through integrated virtual screening and mass spectrometry proteomics.

Journal: European journal of medicinal chemistry

Published: April 22, 2025

JAK3 Inhibitors: Covalent and Noncovalent Interactions of a Cyanamide Group Investigated by Multiscale Free-Energy Simulations.

JAK3 Inhibitors: Covalent and Noncovalent Interactions of a Cyanamide Group Investigated by Multiscale Free-Energy Simulations.

Journal: Journal of chemical information and modeling

Published: January 17, 2025

Spirotetrahydroisoquinoline-Based Histone Deacetylase Inhibitors as New Antifibrotic Agents: Biological Evaluation in Human Fibroblasts from Bronchoalveolar Lavages of Idiopathic Pulmonary Fibrosis Patients.

Spirotetrahydroisoquinoline-Based Histone Deacetylase Inhibitors as New Antifibrotic Agents: Biological Evaluation in Human Fibroblasts from Bronchoalveolar Lavages of Idiopathic Pulmonary Fibrosis Patients.

Journal: ACS pharmacology & translational science

Published: July 26, 2024

Discovery of a new 1-(phenylsulfonyl)-1H-indole derivative targeting the EphA2 receptor with antiproliferative activity on U251 glioblastoma cell line.

Discovery of a new 1-(phenylsulfonyl)-1H-indole derivative targeting the EphA2 receptor with antiproliferative activity on U251 glioblastoma cell line.

Journal: European journal of medicinal chemistry

Published: February 26, 2024

Discovery of novel FGF trap small molecules endowed with anti-myeloma activity.

Discovery of novel FGF trap small molecules endowed with anti-myeloma activity.

Journal: Pharmacological research

Published: December 20, 2023

Molecular Determinants of EphA2 and EphB2 Antagonism Enable the Design of Ligands with Improved Selectivity.

Molecular Determinants of EphA2 and EphB2 Antagonism Enable the Design of Ligands with Improved Selectivity.

Journal: Journal of chemical information and modeling

Published: November 01, 2023

Binding and unbinding of potent melatonin receptor ligands: Mechanistic simulations and experimental evidence.

Binding and unbinding of potent melatonin receptor ligands: Mechanistic simulations and experimental evidence.

Journal: Journal of pineal research

Published: October 12, 2023

Showing 1-12 of 44

Last Updated: 09/26/2026