Lauren B. Arendse
Rondebosch, WC 7701, South Africa
Last Updated: 09/26/2026
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Found 14 publications
Developing kinase inhibitors for malaria: an opportunity or liability?
Journal: Trends in parasitology
Published: April 18, 2023
The anticancer human mTOR inhibitor sapanisertib potently inhibits multiple Plasmodium kinases and life cycle stages.
Journal: Science translational medicine
Published: October 19, 2022
Advances in malaria pharmacology and the online guide to MALARIA PHARMACOLOGY: IUPHAR review 38.
Journal: British journal of pharmacology
Published: May 20, 2022
Probing the Requirements for Dual Angiotensin-Converting Enzyme C-Domain Selective/Neprilysin Inhibition.
Journal: Journal of medicinal chemistry
Published: February 03, 2022
Selective Inhibition of the C-Domain of ACE (Angiotensin-Converting Enzyme) Combined With Inhibition of NEP (Neprilysin): A Potential New Therapy for Hypertension.
Journal: Hypertension (Dallas, Tex. : 1979)
Published: July 26, 2021
Plasmodium Kinases as Potential Drug Targets for Malaria: Challenges and Opportunities.
Journal: ACS infectious diseases
Published: February 16, 2021
New Amidated 3,6-Diphenylated Imidazopyridazines with Potent Antiplasmodium Activity Are Dual Inhibitors of Plasmodium Phosphatidylinositol-4-kinase and cGMP-Dependent Protein Kinase.
Journal: ACS infectious diseases
Published: December 15, 2020
Structural Basis for Inhibitor Potency and Selectivity of Plasmodium falciparum Phosphatidylinositol 4-Kinase Inhibitors.
Journal: ACS infectious diseases
Published: September 23, 2020
Inhibition of Resistance-Refractory P. falciparum Kinase PKG Delivers Prophylactic, Blood Stage, and Transmission-Blocking Antiplasmodial Activity.
Journal: Cell chemical biology
Published: February 15, 2020
Novel Therapeutic Approaches Targeting the Renin-Angiotensin System and Associated Peptides in Hypertension and Heart Failure.
Journal: Pharmacological reviews
Published: September 21, 2019
Structural basis for the C-domain-selective angiotensin-converting enzyme inhibition by bradykinin-potentiating peptide b (BPPb).
Journal: The Biochemical journal
Published: April 15, 2019
Molecular Basis for Multiple Omapatrilat Binding Sites within the ACE C-Domain: Implications for Drug Design.
Journal: Journal of medicinal chemistry
Published: October 30, 2018
Last Updated: 09/26/2026