Laurence H. Patterson

Bradford, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 42 publications

Comprehensive proteome profiling of cytochrome P450 isoforms in cancer models.

Comprehensive proteome profiling of cytochrome P450 isoforms in cancer models.

Journal: Clinical proteomics

Published: May 23, 2025

K562 Chronic Myeloid Leukemia Cells as a Dual β3-Expressing Functional Cell Line Model to Investigate the Effects of Combined αIIbβ3 and αvβ3 Antagonism.

K562 Chronic Myeloid Leukemia Cells as a Dual β3-Expressing Functional Cell Line Model to Investigate the Effects of Combined αIIbβ3 and αvβ3 Antagonism.

Journal: Methods and protocols

Published: March 17, 2025

Sidechain structure-activity relationships of cyclobutane-based small molecule αvβ3 antagonists.

Sidechain structure-activity relationships of cyclobutane-based small molecule αvβ3 antagonists.

Journal: RSC medicinal chemistry

Published: April 29, 2024

Synthesis and Biological Evaluation of Cyclobutane-Based β3 Integrin Antagonists: A Novel Approach to Targeting Integrins for Cancer Therapy.

Synthesis and Biological Evaluation of Cyclobutane-Based β3 Integrin Antagonists: A Novel Approach to Targeting Integrins for Cancer Therapy.

Journal: Cancers

Published: June 15, 2023

Targeting DNA topoisomerase IIα (TOP2A) in the hypoxic tumour microenvironment using unidirectional hypoxia-activated prodrugs (uHAPs).

Targeting DNA topoisomerase IIα (TOP2A) in the hypoxic tumour microenvironment using unidirectional hypoxia-activated prodrugs (uHAPs).

Journal: IUBMB life

Published: January 26, 2022

Active video games and weight management in overweight children and adolescents-systematic review and meta-analysis.

Active video games and weight management in overweight children and adolescents-systematic review and meta-analysis.

Journal: Journal of public health (Oxford, England)

Published: November 04, 2021

OCT2013, an ischaemia-activated antiarrhythmic prodrug, devoid of the systemic side effects of lidocaine.

OCT2013, an ischaemia-activated antiarrhythmic prodrug, devoid of the systemic side effects of lidocaine.

Journal: British journal of pharmacology

Published: June 01, 2021

Probing cytochrome P450 (CYP) bioactivation with chloromethylindoline bioprecursors derived from the duocarmycin family of compounds.

Probing cytochrome P450 (CYP) bioactivation with chloromethylindoline bioprecursors derived from the duocarmycin family of compounds.

Journal: Bioorganic & medicinal chemistry

Published: February 20, 2021

Cytochrome P450 isoforms 1A1, 1B1 AND 2W1 as targets for therapeutic intervention in head and neck cancer.

Cytochrome P450 isoforms 1A1, 1B1 AND 2W1 as targets for therapeutic intervention in head and neck cancer.

Journal: Scientific reports

Published: January 02, 2021

An assay for quantitative analysis of polysialic acid expression in cancer cells.

An assay for quantitative analysis of polysialic acid expression in cancer cells.

Journal: Carbohydrate polymers

Published: November 16, 2020

An efficient assay for identification and quantitative evaluation of potential polysialyltransferase inhibitors.

An efficient assay for identification and quantitative evaluation of potential polysialyltransferase inhibitors.

Journal: The Analyst

Published: May 16, 2020

NLG919/cyclodextrin complexation and anti-cancer therapeutic benefit as a potential immunotherapy in combination with paclitaxel.

NLG919/cyclodextrin complexation and anti-cancer therapeutic benefit as a potential immunotherapy in combination with paclitaxel.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences

Published: May 11, 2019

Showing 1-12 of 42

Last Updated: 09/26/2026