Laurence Ozmen

Basel, BS 4070, Switzerland

Last Updated: 09/26/2026

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Found 17 publications

RO4938581, a GABAA-α5 negative allosteric modulator rescued behavioral and EEG phenotypes of a mouse model of Dup15q syndrome.

RO4938581, a GABAA-α5 negative allosteric modulator rescued behavioral and EEG phenotypes of a mouse model of Dup15q syndrome.

Journal: Molecular psychiatry

Published: October 30, 2024

Microglial response to increasing amyloid load saturates with aging: a longitudinal dual tracer in vivo μPET-study.

Microglial response to increasing amyloid load saturates with aging: a longitudinal dual tracer in vivo μPET-study.

Journal: Journal of neuroinflammation

Published: August 23, 2018

Early and Longitudinal Microglial Activation but Not Amyloid Accumulation Predicts Cognitive Outcome in PS2APP Mice.

Early and Longitudinal Microglial Activation but Not Amyloid Accumulation Predicts Cognitive Outcome in PS2APP Mice.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Published: July 16, 2018

Decreasing the Expression of GABAA α5 Subunit-Containing Receptors Partially Improves Cognitive, Electrophysiological, and Morphological Hippocampal Defects in the Ts65Dn Model of Down Syndrome.

Decreasing the Expression of GABAA α5 Subunit-Containing Receptors Partially Improves Cognitive, Electrophysiological, and Morphological Hippocampal Defects in the Ts65Dn Model of Down Syndrome.

Journal: Molecular neurobiology

Published: March 30, 2017

Region-specific permeability of the blood-brain barrier upon pericyte loss.

Region-specific permeability of the blood-brain barrier upon pericyte loss.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism

Published: March 10, 2017

Increase of TREM2 during Aging of an Alzheimer's Disease Mouse Model Is Paralleled by Microglial Activation and Amyloidosis.

Increase of TREM2 during Aging of an Alzheimer's Disease Mouse Model Is Paralleled by Microglial Activation and Amyloidosis.

Journal: Frontiers in aging neuroscience

Published: October 24, 2016

Trafficking of Endogenous Immunoglobulins by Endothelial Cells at the Blood-Brain Barrier.

Trafficking of Endogenous Immunoglobulins by Endothelial Cells at the Blood-Brain Barrier.

Journal: Scientific reports

Published: October 09, 2015

Passive Tau immunotherapy for prevention of Tau pathology progression

Passive Tau immunotherapy for prevention of Tau pathology progression

Journal: Medecine sciences : M/S

Published: March 07, 2015

Combined treatment with a BACE inhibitor and anti-Aβ antibody gantenerumab enhances amyloid reduction in APPLondon mice.

Combined treatment with a BACE inhibitor and anti-Aβ antibody gantenerumab enhances amyloid reduction in APPLondon mice.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience

Published: August 29, 2014

Neuronal uptake of tau/pS422 antibody and reduced progression of tau pathology in a mouse model of Alzheimer's disease.

Neuronal uptake of tau/pS422 antibody and reduced progression of tau pathology in a mouse model of Alzheimer's disease.

Journal: Brain : a journal of neurology

Published: August 03, 2014

Striatum and entorhinal cortex atrophy in AD mouse models: MRI comprehensive analysis.

Striatum and entorhinal cortex atrophy in AD mouse models: MRI comprehensive analysis.

Journal: Neurobiology of aging

Published: April 04, 2014

β-Secretase (BACE1) inhibitors with high in vivo efficacy suitable for clinical evaluation in Alzheimer's disease.

β-Secretase (BACE1) inhibitors with high in vivo efficacy suitable for clinical evaluation in Alzheimer's disease.

Journal: Journal of medicinal chemistry

Published: April 18, 2013

Showing 1-12 of 17

Last Updated: 09/26/2026