Laurent Roybon

Lund, M 22184, Sweden

Last Updated: 09/26/2026

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Found 55 publications

Transcriptional profiles of immature neurons in aged human hippocampus track Alzheimer's pathology and cognitive resilience.

Transcriptional profiles of immature neurons in aged human hippocampus track Alzheimer's pathology and cognitive resilience.

Journal: Cell stem cell
Published: May 01, 2025

TNFα prevents FGF4-mediated rescue of astrocyte dysfunction and reactivity in human ALS models.

TNFα prevents FGF4-mediated rescue of astrocyte dysfunction and reactivity in human ALS models.

Journal: Neurobiology of disease
Published: May 29, 2024

NPT100-18A rescues mitochondrial oxidative stress and neuronal degeneration in human iPSC-based Parkinson's model.

NPT100-18A rescues mitochondrial oxidative stress and neuronal degeneration in human iPSC-based Parkinson's model.

Journal: BMC neuroscience
Published: May 10, 2024

Inhibition of the serine protease HtrA1 by SerpinE2 suggests an extracellular proteolytic pathway in the control of neural crest migration.

Inhibition of the serine protease HtrA1 by SerpinE2 suggests an extracellular proteolytic pathway in the control of neural crest migration.

Journal: eLife
Published: April 18, 2024

Human iPSC-derived microglia carrying the LRRK2-G2019S mutation show a Parkinson's disease related transcriptional profile and function.

Human iPSC-derived microglia carrying the LRRK2-G2019S mutation show a Parkinson's disease related transcriptional profile and function.

Journal: Scientific reports
Published: July 31, 2023

Proteomic analysis across patient iPSC-based models and human post-mortem hippocampal tissue reveals early cellular dysfunction and progression of Alzheimer's disease pathogenesis.

Proteomic analysis across patient iPSC-based models and human post-mortem hippocampal tissue reveals early cellular dysfunction and progression of Alzheimer's disease pathogenesis.

Journal: Acta neuropathologica communications
Published: June 03, 2023

Human iPSC-Derived Hippocampal Spheroids: An Innovative Tool for Stratifying Alzheimer Disease Patient-Specific Cellular Phenotypes and Developing Therapies.

Human iPSC-Derived Hippocampal Spheroids: An Innovative Tool for Stratifying Alzheimer Disease Patient-Specific Cellular Phenotypes and Developing Therapies.

Journal: Stem cell reports
Published: May 10, 2023

Cellular Aging Secretes: a Comparison of Bone-Marrow-Derived and Induced Mesenchymal Stem Cells and Their Secretome Over Long-Term Culture.

Cellular Aging Secretes: a Comparison of Bone-Marrow-Derived and Induced Mesenchymal Stem Cells and Their Secretome Over Long-Term Culture.

Journal: Stem cell reviews and reports
Published: September 09, 2022

Parkinson's disease and multiple system atrophy patient iPSC-derived oligodendrocytes exhibit alpha-synuclein-induced changes in maturation and immune reactive properties.

Parkinson's disease and multiple system atrophy patient iPSC-derived oligodendrocytes exhibit alpha-synuclein-induced changes in maturation and immune reactive properties.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: March 16, 2022

Canonical Bone Morphogenetic Protein Signaling Regulates Expression of Aquaporin-4 and Its Anchoring Complex in Mouse Astrocytes.

Canonical Bone Morphogenetic Protein Signaling Regulates Expression of Aquaporin-4 and Its Anchoring Complex in Mouse Astrocytes.

Journal: Frontiers in cellular neuroscience
Published: February 17, 2022

Human iPSC-derived hippocampal spheroids: An innovative tool for stratifying Alzheimer disease patient-specific cellular phenotypes and developing therapies.

Human iPSC-derived hippocampal spheroids: An innovative tool for stratifying Alzheimer disease patient-specific cellular phenotypes and developing therapies.

Journal: Stem cell reports
Published: November 10, 2021

The intracellular milieu of Parkinson's disease patient brain cells modulates alpha-synuclein protein aggregation.

The intracellular milieu of Parkinson's disease patient brain cells modulates alpha-synuclein protein aggregation.

Journal: Acta neuropathologica communications
Published: August 02, 2021
Showing 1-12 of 55

Last Updated: 09/26/2026