Last Updated: 09/26/2026
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Found 44 publications
Comprehensive in vitro assessment of drug-drug interactions of the major human metabolite of soticlestat.
Journal: Xenobiotica; the fate of foreign compounds in biological systems
Published: July 15, 2025
Physiologically Based Pharmacokinetic Modeling to Predict Drug-Drug Interactions of Soticlestat as a Victim of CYP Induction and Inhibition, and as a Perpetrator of CYP and P-Glycoprotein Inhibition.
Journal: Clinical pharmacology in drug development
Published: October 21, 2024
Metabolism and Excretion of [14C]Mobocertinib, a Selective Covalent Inhibitor of Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion Mutations, in Healthy Male Subjects.
Journal: Drug metabolism and disposition: the biological fate of chemicals
Published: June 12, 2024
Longitudinal imaging of therapeutic enzyme expression after gene therapy for Fabry disease using positron emission tomography and the radiotracer [18F]AGAL.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy
Published: April 15, 2024
Radiosynthesis and Early Evaluation of a Positron Emission Tomography Imaging Probe [18F]AGAL Targeting Alpha-Galactosidase A Enzyme for Fabry Disease.
Journal: Molecules (Basel, Switzerland)
Published: September 20, 2023
Amplification of olfactory signals by Anoctamin 9 is important for mammalian olfaction.
Journal: Progress in neurobiology
Published: May 21, 2022
Conserved Amino Acids Residing Outside the Voltage Field Can Shift the Voltage Sensitivity and Increase the Signal Speed and Size of Ciona Based GEVIs.
Journal: Frontiers in cell and developmental biology
Published: February 02, 2022
Metabolism and Disposition of [14C]Pevonedistat, a First-in-Class NEDD8-Activating Enzyme Inhibitor, after Intravenous Infusion to Patients with Advanced Solid Tumors.
Journal: Drug metabolism and disposition: the biological fate of chemicals
Published: January 27, 2022
Voltage imaging in the olfactory bulb using transgenic mouse lines expressing the genetically encoded voltage indicator ArcLight.
Journal: Scientific reports
Published: September 13, 2021
The Mammalian Olfactory Bulb Contributes to the Adaptation of Odor Responses: A Second Perceptual Computation Carried Out by the Bulb.
Journal: eNeuro
Published: July 29, 2021
Sinusoidal Uptake Determines the Hepatic Clearance of Pevonedistat (TAK-924) as Explained by Extended Clearance Model.
Journal: Drug metabolism and disposition: the biological fate of chemicals
Published: January 20, 2021
Biotransformation Pathways and Metabolite Profiles of Oral [14C]Alisertib (MLN8237), an Investigational Aurora A Kinase Inhibitor, in Patients with Advanced Solid Tumors.
Journal: Drug metabolism and disposition: the biological fate of chemicals
Published: March 29, 2019
Last Updated: 09/26/2026