Le Sun - Publications

Minimal Physiologically-Based Pharmacokinetic Modeling to Predict Concentration-Time Profiles of Poorly Soluble Cinacalcet Hydrochloride in Fasting and Fed State.

Journal: European journal of drug metabolism and pharmacokinetics

Published: August 01, 2025

Prediction of in vivo behavior of nanoparticles using physiologically based pharmacokinetic model: The modeling approach and issues.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

Published: January 27, 2025

Cyclodextrin-based delivery systems for chemical and genetic drugs: Current status and future.

Journal: Carbohydrate polymers

Published: October 10, 2024

PBPK model of pegylated liposomal doxorubicin to simultaneously predict the concentration-time profile of encapsulated and free doxorubicin in tissues.

Journal: Drug delivery and translational research

Published: July 20, 2024

Physiologically Based Pharmacokinetic Modeling of Cefadroxil in Mouse, Rat, and Human to Predict Concentration-Time Profile at Infected Tissue.

Journal: Frontiers in pharmacology

Published: April 09, 2021

Correlation Between Arrhythmia and the Prognosis in Children With EFE/LVNC/DCM.

Journal: Frontiers in pediatrics

Published: August 19, 2019

A physiologically based pharmacokinetic model for valacyclovir established based on absolute expression quantity of hPEPT1 and its application.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences

Published: April 15, 2018

The Solubility-Permeability Trade-Off of Progesterone With Cyclodextrins Under Physiological Conditions: Experimental Observations and Computer Simulations.

Journal: Journal of pharmaceutical sciences

Published: April 13, 2017

Exploring the Feasibility of Biowaiver Extension of BCS Class III Drugs with Site-Specific Absorption Using Gastrointestinal Simulation Technology.

Journal: European journal of drug metabolism and pharmacokinetics

Published: July 23, 2016