Lea C. Rodriguez

Quebec, QC, Canada

Last Updated: 09/26/2026

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Found 20 publications

Low-penetrance TP53 variants are mainly hypomorphic: an underestimated issue with high clinical significance.

Low-penetrance TP53 variants are mainly hypomorphic: an underestimated issue with high clinical significance.

Journal: NPJ genomic medicine
Published: September 20, 2025

Misclassification of TP53 germline variants: implications for survival analysis in AML transplant studies.

Misclassification of TP53 germline variants: implications for survival analysis in AML transplant studies.

Journal: Leukemia
Published: August 05, 2025

Noradrenergic signaling controls Alzheimer's disease pathology via activation of microglial β2 adrenergic receptors.

Noradrenergic signaling controls Alzheimer's disease pathology via activation of microglial β2 adrenergic receptors.

Journal: Brain, behavior, and immunity
Published: April 09, 2024

A Role for the V0 Sector of the V-ATPase in Neuroexocytosis: Exogenous V0d Blocks Complexin and SNARE Interactions with V0c.

A Role for the V0 Sector of the V-ATPase in Neuroexocytosis: Exogenous V0d Blocks Complexin and SNARE Interactions with V0c.

Journal: Cells
Published: February 07, 2023

TREM2-independent microgliosis promotes tau-mediated neurodegeneration in the presence of ApoE4.

TREM2-independent microgliosis promotes tau-mediated neurodegeneration in the presence of ApoE4.

Journal: Neuron
Published: June 21, 2022

B cell-dependent EAE induces visual deficits in the mouse with similarities to human autoimmune demyelinating diseases.

B cell-dependent EAE induces visual deficits in the mouse with similarities to human autoimmune demyelinating diseases.

Journal: Journal of neuroinflammation
Published: November 26, 2021

Gene Therapy Strategy for Alzheimer's and Parkinson's Diseases Aimed at Preventing the Formation of Neurotoxic Oligomers in SH-SY5Y Cells.

Gene Therapy Strategy for Alzheimer's and Parkinson's Diseases Aimed at Preventing the Formation of Neurotoxic Oligomers in SH-SY5Y Cells.

Journal: International journal of molecular sciences
Published: September 28, 2021

The Lack of Amyloidogenic Activity Is Persistent in Old WT and APPswe/PS1ΔE9 Mouse Retinae.

The Lack of Amyloidogenic Activity Is Persistent in Old WT and APPswe/PS1ΔE9 Mouse Retinae.

Journal: International journal of molecular sciences
Published: September 15, 2021

Role of Retinoid X Receptors (RXRs) and dietary vitamin A in Alzheimer's disease: Evidence from clinicopathological and preclinical studies.

Role of Retinoid X Receptors (RXRs) and dietary vitamin A in Alzheimer's disease: Evidence from clinicopathological and preclinical studies.

Journal: Neurobiology of disease
Published: December 07, 2020

Tau Gene Deletion does not Influence Axonal Regeneration and Retinal Neuron Survival in the Injured Mouse Visual System.

Tau Gene Deletion does not Influence Axonal Regeneration and Retinal Neuron Survival in the Injured Mouse Visual System.

Journal: International journal of molecular sciences
Published: May 09, 2020

Tau modulates visual plasticity in adult and old mice.

Tau modulates visual plasticity in adult and old mice.

Journal: Neurobiology of aging
Published: April 04, 2020

Nogo-A-targeting antibody promotes visual recovery and inhibits neuroinflammation after retinal injury.

Nogo-A-targeting antibody promotes visual recovery and inhibits neuroinflammation after retinal injury.

Journal: Cell death & disease
Published: September 13, 2019
Showing 1-12 of 20

Last Updated: 09/26/2026