Leda M. Barrios-Castano

Pelotas, RS, Brazil

Last Updated: 09/26/2026

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Found 9 publications

Diagnostic Accuracy of the TR Chagas Bio-Manguinhos Rapid Test in the Municipality of Canguçu, Rio Grande do Sul, a Historically Endemic Area for Chagas Disease in Southern Brazil: a prospective study.

Diagnostic Accuracy of the TR Chagas Bio-Manguinhos Rapid Test in the Municipality of Canguçu, Rio Grande do Sul, a Historically Endemic Area for Chagas Disease in Southern Brazil: a prospective study.

Journal: Acta tropica

Published: May 13, 2026

Benznidazole therapy improves pressure overload and cardiac electrical profile in an experimental model of Angiotensin II infusion-induced hypertension: Mechanistic insights.

Benznidazole therapy improves pressure overload and cardiac electrical profile in an experimental model of Angiotensin II infusion-induced hypertension: Mechanistic insights.

Journal: PloS one

Published: August 13, 2025

Benznidazole therapy improves pressure overload and cardiac electrical profile in an experimental model of Angiotensin II infusion-induced hypertension: Mechanistic insights.

Benznidazole therapy improves pressure overload and cardiac electrical profile in an experimental model of Angiotensin II infusion-induced hypertension: Mechanistic insights.

Journal: PloS one

Published: August 13, 2025

Diagnostic Performance of Chimeric Recombinant Antigens of Trypanosoma cruzi for Identifying Chagas Disease in Samples From Rio Grande do Sul.

Diagnostic Performance of Chimeric Recombinant Antigens of Trypanosoma cruzi for Identifying Chagas Disease in Samples From Rio Grande do Sul.

Journal: Tropical medicine & international health : TM & IH

Published: April 29, 2025

Combined benznidazole and pentoxifylline therapy improves behavioral and cognitive changes in association with the regulation of systemic inflammatory profile in chronic experimental Chagas disease.

Combined benznidazole and pentoxifylline therapy improves behavioral and cognitive changes in association with the regulation of systemic inflammatory profile in chronic experimental Chagas disease.

Journal: PloS one

Published: December 19, 2024

The beneficial effect of fluoxetine on behavioral and cognitive changes in chronic experimental Chagas disease unveils the role of serotonin fueling astrocyte infection by Trypanosoma cruzi.

The beneficial effect of fluoxetine on behavioral and cognitive changes in chronic experimental Chagas disease unveils the role of serotonin fueling astrocyte infection by Trypanosoma cruzi.

Journal: PLoS neglected tropical diseases

Published: July 13, 2023

Drug Repurposing in Chagas Disease: Chloroquine Potentiates Benznidazole Activity against Trypanosoma cruzi In Vitro and In Vivo.

Drug Repurposing in Chagas Disease: Chloroquine Potentiates Benznidazole Activity against Trypanosoma cruzi In Vitro and In Vivo.

Journal: Antimicrobial agents and chemotherapy

Published: October 31, 2022

Behavioral alterations in long-term Toxoplasma gondii infection of C57BL/6 mice are associated with neuroinflammation and disruption of the blood brain barrier.

Behavioral alterations in long-term Toxoplasma gondii infection of C57BL/6 mice are associated with neuroinflammation and disruption of the blood brain barrier.

Journal: PloS one

Published: May 18, 2021

Memory impairment in chronic experimental Chagas disease: Benznidazole therapy reversed cognitive deficit in association with reduction of parasite load and oxidative stress in the nervous tissue.

Memory impairment in chronic experimental Chagas disease: Benznidazole therapy reversed cognitive deficit in association with reduction of parasite load and oxidative stress in the nervous tissue.

Journal: PloS one

Published: October 25, 2020

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Last Updated: 09/26/2026