Leen Mathys

Leuven, VLG 3000, Belgium

Last Updated: 09/26/2026

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Found 10 publications

Potent antiviral activity of carbohydrate-specific algal and leguminous lectins from the Brazilian biodiversity.

Potent antiviral activity of carbohydrate-specific algal and leguminous lectins from the Brazilian biodiversity.

Journal: MedChemComm

Published: October 08, 2018

Tryptophan dendrimers that inhibit HIV replication, prevent virus entry and bind to the HIV envelope glycoproteins gp120 and gp41.

Tryptophan dendrimers that inhibit HIV replication, prevent virus entry and bind to the HIV envelope glycoproteins gp120 and gp41.

Journal: European journal of medicinal chemistry

Published: July 31, 2015

The Cellular Thioredoxin-1/Thioredoxin Reductase-1 Driven Oxidoreduction Represents a Chemotherapeutic Target for HIV-1 Entry Inhibition.

The Cellular Thioredoxin-1/Thioredoxin Reductase-1 Driven Oxidoreduction Represents a Chemotherapeutic Target for HIV-1 Entry Inhibition.

Journal: PloS one

Published: July 22, 2015

The role of cellular oxidoreductases in viral entry and virus infection-associated oxidative stress: potential therapeutic applications.

The role of cellular oxidoreductases in viral entry and virus infection-associated oxidative stress: potential therapeutic applications.

Journal: Expert opinion on therapeutic targets

Published: July 17, 2015

Several N-Glycans on the HIV Envelope Glycoprotein gp120 Preferentially Locate Near Disulphide Bridges and Are Required for Efficient Infectivity and Virus Transmission.

Several N-Glycans on the HIV Envelope Glycoprotein gp120 Preferentially Locate Near Disulphide Bridges and Are Required for Efficient Infectivity and Virus Transmission.

Journal: PloS one

Published: March 06, 2015

Anti-HIV-1 activity of a tripodal receptor that recognizes mannose oligomers.

Anti-HIV-1 activity of a tripodal receptor that recognizes mannose oligomers.

Journal: European journal of medicinal chemistry

Published: January 22, 2015

The role of N-glycans of HIV-1 gp41 in virus infectivity and susceptibility to the suppressive effects of carbohydrate-binding agents.

The role of N-glycans of HIV-1 gp41 in virus infectivity and susceptibility to the suppressive effects of carbohydrate-binding agents.

Journal: Retrovirology

Published: May 28, 2014

Deletion of the highly conserved N-glycan at Asn260 of HIV-1 gp120 affects folding and lysosomal degradation of gp120, and results in loss of viral infectivity.

Deletion of the highly conserved N-glycan at Asn260 of HIV-1 gp120 affects folding and lysosomal degradation of gp120, and results in loss of viral infectivity.

Journal: PloS one

Published: April 28, 2014

Exposure of HIV-1 to a combination of two carbohydrate-binding agents markedly delays drug resistance development and selects for virus strains with compromised fitness.

Exposure of HIV-1 to a combination of two carbohydrate-binding agents markedly delays drug resistance development and selects for virus strains with compromised fitness.

Journal: The Journal of antimicrobial chemotherapy

Published: October 23, 2013

Inhibition of infection and transmission of HIV-1 and lack of significant impact on the vaginal commensal lactobacilli by carbohydrate-binding agents.

Inhibition of infection and transmission of HIV-1 and lack of significant impact on the vaginal commensal lactobacilli by carbohydrate-binding agents.

Journal: The Journal of antimicrobial chemotherapy

Published: May 04, 2013

Showing 1-10 of 10

Last Updated: 09/26/2026