Lei Du

Jiangsu Key Laboratory Of New Drug Research And Clinical Pharmacy
Xuzhou, 221004, China

Last Updated: 09/26/2026

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Found 48 publications

Shikonin alleviates renal tubulointerstitial fibrosis in diabetic nephropathy via CCR5/ TGF-β1 signaling axis mediating EMT.

Shikonin alleviates renal tubulointerstitial fibrosis in diabetic nephropathy via CCR5/ TGF-β1 signaling axis mediating EMT.

Journal: European journal of pharmacology

Published: July 01, 2025

Swietenolide inhibits the TXNIP/NLRP3 pathways via Nrf2 activation to ameliorate cognitive dysfunction in diabetic mice.

Swietenolide inhibits the TXNIP/NLRP3 pathways via Nrf2 activation to ameliorate cognitive dysfunction in diabetic mice.

Journal: Neuropharmacology

Published: November 11, 2024

Prrx1 promotes mesangial cell proliferation and kidney fibrosis through YAP in diabetic nephropathy.

Prrx1 promotes mesangial cell proliferation and kidney fibrosis through YAP in diabetic nephropathy.

Journal: Journal of pharmaceutical analysis

Published: November 07, 2024

GABP Promotes Mesangial Cell Proliferation and Renal Fibrosis Through GLI1 in Diabetic Nephropathy.

GABP Promotes Mesangial Cell Proliferation and Renal Fibrosis Through GLI1 in Diabetic Nephropathy.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: July 03, 2024

LncRNA KIFAP3-5:1 inhibits epithelial-mesenchymal transition of renal tubular cell through PRRX1 in diabetic nephropathy.

LncRNA KIFAP3-5:1 inhibits epithelial-mesenchymal transition of renal tubular cell through PRRX1 in diabetic nephropathy.

Journal: Cell biology and toxicology

Published: January 14, 2024

Downregulation of Sirt3 contributes to β-cell dedifferentiation via FoxO1 in type 2 diabetic mellitus.

Downregulation of Sirt3 contributes to β-cell dedifferentiation via FoxO1 in type 2 diabetic mellitus.

Journal: Acta diabetologica

Published: May 29, 2023

16α-OHE1, a novel oestrogen metabolite, attenuates dysfunction of left ventricle contractility via regulation of autophagy after myocardial ischemia and reperfusion.

16α-OHE1, a novel oestrogen metabolite, attenuates dysfunction of left ventricle contractility via regulation of autophagy after myocardial ischemia and reperfusion.

Journal: International journal of cardiology

Published: March 05, 2023

Inhibition of S100A8/A9 ameliorates renal interstitial fibrosis in diabetic nephropathy.

Inhibition of S100A8/A9 ameliorates renal interstitial fibrosis in diabetic nephropathy.

Journal: Metabolism: clinical and experimental

Published: September 28, 2022

Decreased Sirt3 contributes to cyclic production of reactive oxygen species and islet β-cell apoptosis in high glucose conditions.

Decreased Sirt3 contributes to cyclic production of reactive oxygen species and islet β-cell apoptosis in high glucose conditions.

Journal: Molecular biology reports

Published: May 24, 2022

Corrigendum to 'Targeting mammalian serine/threonine-protein kinase 4 through yes-associated protein/TEA domain transcription factor-mediated epithelial-mesenchymal transition ameliorates diabetic nephropathy orchestrated renal fibrosis [Metabolism Clinical and Experimental 108 (2020) 154258].

Corrigendum to 'Targeting mammalian serine/threonine-protein kinase 4 through yes-associated protein/TEA domain transcription factor-mediated epithelial-mesenchymal transition ameliorates diabetic nephropathy orchestrated renal fibrosis [Metabolism Clinical and Experimental 108 (2020) 154258].

Journal: Metabolism: clinical and experimental

Published: March 15, 2022

Correction to: Novel biphenyl diester derivative AB-38b inhibits NLRP3 inflammasome through Nrf2 activation in diabetic nephropathy.

Correction to: Novel biphenyl diester derivative AB-38b inhibits NLRP3 inflammasome through Nrf2 activation in diabetic nephropathy.

Journal: Cell biology and toxicology

Published: February 16, 2022

Author Correction: Inactivation of TSC1 promotes epithelial-mesenchymal transition of renal tubular epithelial cells in mouse diabetic nephropathy.

Author Correction: Inactivation of TSC1 promotes epithelial-mesenchymal transition of renal tubular epithelial cells in mouse diabetic nephropathy.

Journal: Acta pharmacologica Sinica

Published: October 14, 2021

Showing 1-12 of 48

Last Updated: 09/26/2026