Leif Hultin

AstraZeneca R&D
Moelndal, O, Sweden

Last Updated: 09/26/2026

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Found 15 publications

Targeted Delivery of mRNA to the Heart via Extracellular Vesicles or Lipid Nanoparticles.

Targeted Delivery of mRNA to the Heart via Extracellular Vesicles or Lipid Nanoparticles.

Journal: Journal of extracellular vesicles

Published: December 15, 2025

Spirocyclopentane as a Novel Scaffold for Potent Ghrelin Receptor Full Agonists.

Spirocyclopentane as a Novel Scaffold for Potent Ghrelin Receptor Full Agonists.

Journal: Journal of medicinal chemistry

Published: December 05, 2025

Hybrid Extracellular Vesicles for Efficient Loading and Functional Delivery of mRNA.

Hybrid Extracellular Vesicles for Efficient Loading and Functional Delivery of mRNA.

Journal: Journal of extracellular vesicles

Published: April 11, 2025

Barcoded Hybrids of Extracellular Vesicles and Lipid Nanoparticles for Multiplexed Analysis of Tissue Distribution.

Barcoded Hybrids of Extracellular Vesicles and Lipid Nanoparticles for Multiplexed Analysis of Tissue Distribution.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: July 10, 2024

The Combination of Vascular Endothelial Growth Factor A (VEGF-A) and Fibroblast Growth Factor 1 (FGF1) Modified mRNA Improves Wound Healing in Diabetic Mice: An Ex Vivo and In Vivo Investigation.

The Combination of Vascular Endothelial Growth Factor A (VEGF-A) and Fibroblast Growth Factor 1 (FGF1) Modified mRNA Improves Wound Healing in Diabetic Mice: An Ex Vivo and In Vivo Investigation.

Journal: Cells

Published: January 09, 2024

Lipid Nanoparticles Deliver the Therapeutic VEGFA mRNA In Vitro and In Vivo and Transform Extracellular Vesicles for Their Functional Extensions.

Lipid Nanoparticles Deliver the Therapeutic VEGFA mRNA In Vitro and In Vivo and Transform Extracellular Vesicles for Their Functional Extensions.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: October 23, 2022

Towards fully automated segmentation of rat cardiac MRI by leveraging deep learning frameworks.

Towards fully automated segmentation of rat cardiac MRI by leveraging deep learning frameworks.

Journal: Scientific reports

Published: September 08, 2021

Identification and Optimization of Pyrrolidine Derivatives as Highly Potent Ghrelin Receptor Full Agonists.

Identification and Optimization of Pyrrolidine Derivatives as Highly Potent Ghrelin Receptor Full Agonists.

Journal: Journal of medicinal chemistry

Published: August 14, 2020

Functionalized lipid nanoparticles for subcutaneous administration of mRNA to achieve systemic exposures of a therapeutic protein.

Functionalized lipid nanoparticles for subcutaneous administration of mRNA to achieve systemic exposures of a therapeutic protein.

Journal: Molecular therapy. Nucleic acids

Published: July 11, 2020

Identification and Pharmacological Profile of an Indane Based Series of Ghrelin Receptor Full Agonists.

Identification and Pharmacological Profile of an Indane Based Series of Ghrelin Receptor Full Agonists.

Journal: Journal of medicinal chemistry

Published: June 19, 2018

Pharmacological modulation of colorectal distension evoked potentials in conscious rats.

Pharmacological modulation of colorectal distension evoked potentials in conscious rats.

Journal: Neuropharmacology

Published: February 26, 2018

Rheumatic Disease: Protease-Activated Receptor-2 in Synovial Joint Pathobiology.

Rheumatic Disease: Protease-Activated Receptor-2 in Synovial Joint Pathobiology.

Journal: Frontiers in endocrinology

Published: January 25, 2018

Showing 1-12 of 15

Last Updated: 09/26/2026