Leila M. Luheshi

Lensfield Road
Cambridge, ENG CB21EW, United Kingdom

Last Updated: 09/26/2026

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Found 11 publications

Clusterin protects neurons against intracellular proteotoxicity.

Clusterin protects neurons against intracellular proteotoxicity.

Journal: Acta neuropathologica communications

Published: October 10, 2017

Moving pathogen genomics out of the lab and into the clinic: what will it take?

Moving pathogen genomics out of the lab and into the clinic: what will it take?

Journal: Genome medicine

Published: January 01, 2016

Big data or bust: realizing the microbial genomics revolution.

Big data or bust: realizing the microbial genomics revolution.

Journal: Microbial genomics

Published: December 11, 2015

Intercellular propagated misfolding of wild-type Cu/Zn superoxide dismutase occurs via exosome-dependent and -independent mechanisms.

Intercellular propagated misfolding of wild-type Cu/Zn superoxide dismutase occurs via exosome-dependent and -independent mechanisms.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: February 20, 2014

Oligomer-targeting with a conformational antibody fragment promotes toxicity in Aβ-expressing flies.

Oligomer-targeting with a conformational antibody fragment promotes toxicity in Aβ-expressing flies.

Journal: Acta neuropathologica communications

Published: February 04, 2014

Single point mutations induce a switch in the molecular mechanism of the aggregation of the Alzheimer's disease associated Aβ42 peptide.

Single point mutations induce a switch in the molecular mechanism of the aggregation of the Alzheimer's disease associated Aβ42 peptide.

Journal: ACS chemical biology

Published: November 09, 2013

Direct observations of amyloid β self-assembly in live cells provide insights into differences in the kinetics of Aβ(1-40) and Aβ(1-42) aggregation.

Direct observations of amyloid β self-assembly in live cells provide insights into differences in the kinetics of Aβ(1-40) and Aβ(1-42) aggregation.

Journal: Chemistry & biology

Published: November 06, 2013

Proliferation of amyloid-β42 aggregates occurs through a secondary nucleation mechanism.

Proliferation of amyloid-β42 aggregates occurs through a secondary nucleation mechanism.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: May 25, 2013

Selenium-enhanced electron microscopic imaging of different aggregate forms of a segment of the amyloid β peptide in cells.

Selenium-enhanced electron microscopic imaging of different aggregate forms of a segment of the amyloid β peptide in cells.

Journal: ACS nano

Published: May 29, 2012

Expression in drosophila of tandem amyloid β peptides provides insights into links between aggregation and neurotoxicity.

Expression in drosophila of tandem amyloid β peptides provides insights into links between aggregation and neurotoxicity.

Journal: The Journal of biological chemistry

Published: March 31, 2012

The aggregation and neurotoxicity of TDP-43 and its ALS-associated 25 kDa fragment are differentially affected by molecular chaperones in Drosophila.

The aggregation and neurotoxicity of TDP-43 and its ALS-associated 25 kDa fragment are differentially affected by molecular chaperones in Drosophila.

Journal: PloS one

Published: October 24, 2011

Showing 1-11 of 11

Last Updated: 09/26/2026